| Quantity | 20 nmol, 50 nmol, 100 nmol, 200 nmol | 1 | 1.5 million cells & Neural Plating-XF Medium | Inquire | 20 nmol, 50 nmol, 100 nmol, 200 nmol |
| Description | The product SIRGT75561WQ is a type of small interfering RNA (siRNA) that targets NTM gene and regulates the expression of gene. The siRNA interferes with the expression of NTM gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has potentialThe product SIRGT75561WQ is a type of small interfering RNA (siRNA) that targets NTM gene and regulates the expression of gene. The siRNA interferes with the expression of NTM gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More | Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from normal Cynomolgus monkey brain Vascular tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from normal Cynomolgus monkey brain Vascular tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as cell-cell interaction, adhesion, migration, PCR, Western blot, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in autosomal-dominant familial Parkinson's disease with late onset (Fonzo et al., 2006, Thaler et al., 2009). The G2019S mutation increases the kinase activity of LRRK2 causing increased autophosphorylation and substrate phosphorylation that may affect neuronal cell health in Parkinson's disease patients (West et al., 2005).... Read More | Marmoset monkeys are tree-dwelling small monkeys that habitat South American. This product is isolated from Marmosets Fallopian Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, Marmoset monkeys are tree-dwelling small monkeys that habitat South American. This product is isolated from Marmosets Fallopian Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry.... Read More | The product SIRGT47166WQ-2F is a type of small interfering RNA (siRNA) that targets LIN28A gene and regulates the expression of gene. The siRNA interferes with the expression of LIN28A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The The product SIRGT47166WQ-2F is a type of small interfering RNA (siRNA) that targets LIN28A gene and regulates the expression of gene. The siRNA interferes with the expression of LIN28A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2_-deoxy-2_-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |