| Description | The product SIRGT99141WQ-LNA is a type of small interfering RNA (siRNA) that targets Kiz gene and regulates the expression of gene. The siRNA interferes with the expression of Kiz gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA isThe product SIRGT99141WQ-LNA is a type of small interfering RNA (siRNA) that targets Kiz gene and regulates the expression of gene. The siRNA interferes with the expression of Kiz gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More | Cynomolgus Monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from Cynomolgus Monkey fresh bone marrow under sterile conditions. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of Cynomolgus Monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from Cynomolgus Monkey fresh bone marrow under sterile conditions. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of applications, including drug discovery, assay validation/development, and immunology based assays.... Read More | Creative Biolabs' Neuropathy Frozen Tissue Panels are designed for the study of Alzheimer's disease, Parkinson's disease, dementia, multiple sclerosis, progressive supranuclear palsy (PSP) and depression. | Creative Biolabs' Neuropathy Frozen Tissue Panels are designed for the study of Alzheimer's disease, Parkinson's disease, dementia, multiple sclerosis, progressive supranuclear palsy (PSP) and depression. | Creative Biolabs Human iPSC-Sensory Neuron Progenitors are derived from integration-free iPSCs and have been differentiated to neurons using small molecules. We offer a fully optimized cell culture system including tailored Sensory Maintenance Medium and coating reagents to promote the viability andCreative Biolabs Human iPSC-Sensory Neuron Progenitors are derived from integration-free iPSCs and have been differentiated to neurons using small molecules. We offer a fully optimized cell culture system including tailored Sensory Maintenance Medium and coating reagents to promote the viability and maturation of sensory neurons for endpoint assays on glass or plastic.
Our iPSC-derived sensory neurons express several voltage-gated sodium ion channels and transient receptor potential (TRP) ion channels that play a key role in nociception. These include sodium ion channels Nav1.7 and the DRG-specific, TTX-resistant channels, Nav1.8 and Nav1.9 as well as the temperature-sensitive, TRPV1 and TRPM8, and TRPA1, a sensor of pungency, bitterness and cold.
Creative Biolabs iPSC-Derived Sensory Neuron Progenitors are available in large batch sizes for reliable and consistent results in high-throughput screening assays. The cells are also suitable for investigating disorders of the peripheral nervous system and chronic pain as well as drug targets for pain relief.... Read More |