| Description | Rhesus monkey is widely used in medical and biological research on human and animal related diseases even space travel due to its closeness to the human anatomically and physiologically. This product is isolated from Rhesus monkeys Diaphragm Tissue. The sample is negative for Herpes-B Virus, as wellRhesus monkey is widely used in medical and biological research on human and animal related diseases even space travel due to its closeness to the human anatomically and physiologically. This product is isolated from Rhesus monkeys Diaphragm Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry.... Read More | Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from normal Cynomolgus monkey prostate tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from normal Cynomolgus monkey prostate tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as cell-cell interaction, adhesion, migration, PCR, Western blot, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and further details.
The P301L mutation MAPT has been implicated in frontotemporal dementia and parkinsonism (Dumanchin et al., 1998). The mutation affects only the 4R isoforms of MAPT since the exon containing the mutation is spliced out of 3R isoforms (Hutton et al., 1998). Aggregated MAPT/tau protein in affected patients consisted mainly of the 4R isoform (Hutton et al., 1998). The P301L mutation promotes aggregation of MAPT/tau protein into ordered paired helical filaments and beta sheet formation in vitro (von Bergen et al., 2001).... Read More | Lactobacillus species are normal flora of the human mouth, gastrointestinal tract, and female genital tract, where they produce lactic acid and competitively inhibit pathogenic organisms. Lactobacillus are small, slender, nonmotile, Gram-positive bacilli in chains. Immature colonies appear smooth, Lactobacillus species are normal flora of the human mouth, gastrointestinal tract, and female genital tract, where they produce lactic acid and competitively inhibit pathogenic organisms. Lactobacillus are small, slender, nonmotile, Gram-positive bacilli in chains. Immature colonies appear smooth, convex, and translucent. Some species of Lactobacillus used commonly as probiotics. They are most commonly used for diarrhea, including infectious diarrhea and diarrhea in people taking antibiotics. Some people also use lactobacillus for general digestion problems, irritable bowel syndrome; IBS, colic in infants, and many other conditions that involve the stomach and bowel.... Read More | Rat Schwann cells (RSC) are the main glial cells in the peripheral nervous system, providing physical and chemical support for neurons. Myelin Schwann cells form an insulating sheath around neuron cell bodies (sensory ganglia) and fibers (sensory nerves and motor neurons). Regular exposure of the Rat Schwann cells (RSC) are the main glial cells in the peripheral nervous system, providing physical and chemical support for neurons. Myelin Schwann cells form an insulating sheath around neuron cell bodies (sensory ganglia) and fibers (sensory nerves and motor neurons). Regular exposure of the axon membrane to the extracellular space (myelin sheath space) at the Raniver node allows the action potential to propagate quickly along the axon. RSC is important for the morphology, survival and growth of axons and neurons. Studies have also shown that Schwann cells can promote neuronal recovery and experimental spinal cord regeneration.... Read More |