| Description | DescriptionLinear double-stranded lambda bacteriophage (cI857 Sam7) DNA, 48502 base pairs with a molecular weight of 31.5 106 Da. Isolated from a heat-inducible lysogenic E.coli W3110 strain. GeneBank/EMBL accession numbers NC_001416, M17233, M24325, V00636, X00906. Applications Activity DescriptionLinear double-stranded lambda bacteriophage (cI857 Sam7) DNA, 48502 base pairs with a molecular weight of 31.5 106 Da. Isolated from a heat-inducible lysogenic E.coli W3110 strain. GeneBank/EMBL accession numbers NC_001416, M17233, M24325, V00636, X00906. Applications Activity and specificity assays of restriction enzymes. Preparation of DNA molecular weight standards. Cloning.Storage Buffer 10 mM Tris-HCl (pH 7.6) and 1 mM EDTA.Source :E. coli... Read More | Inquire | Biochemical Test:SDS-PAGE (purity > 80%); Western blot with patient sample.Calculated Isoelectric Point:pH 6.64 | Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description: DCX (doublecortin, N-GST chimera)contains 2 doublecortin domains and belongs to the doublecortin family. It is highly expressed in neuronal cells of fetal brain, but not expressed in other fetal tissues. In the Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description: DCX (doublecortin, N-GST chimera)contains 2 doublecortin domains and belongs to the doublecortin family. It is highly expressed in neuronal cells of fetal brain, but not expressed in other fetal tissues. In the adult, it is highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas. DCX is a microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. It may act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. DCX may in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. It may be part with LIS-1 of a overlapping, but distinct, signaling pathways that promote neuronal migration. Defects in DCX are the cause of lissencephaly X-linked type 1 and subcortical band heterotopia X-linked... Read More | Inquire |