| Description | Protease is an enzyme used to break down proteins by hydrolyzing peptide bonds. Protease is used to degrade proteins, to study protease inhibitors and to study thermal inactivation kinetics. Protease is used in nucleic acid isolation procedures in incubations. Protease from Bacillus Protease is an enzyme used to break down proteins by hydrolyzing peptide bonds. Protease is used to degrade proteins, to study protease inhibitors and to study thermal inactivation kinetics. Protease is used in nucleic acid isolation procedures in incubations. Protease from Bacillus amyloliquefaciens has been used for the unhairing of hides and skins. It has also been used in a study to investigate peptide bond formation using the carbamoylmethyl ester as the acyl donor... Read More | Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs.Form:Solid | Neuropeptide Y (13-36), amide, human is a selective neuropeptide Y 2 receptor agonist.In VivoNeuropeptide Y (13-36) (intraventricular injection; 25-3000 pmol) produces a dose-dependent increase (up to 14%; ED 50 value of 0.3 nmol for overall effects and 0.97 nmol for the peak effects) in mean Neuropeptide Y (13-36), amide, human is a selective neuropeptide Y 2 receptor agonist.In VivoNeuropeptide Y (13-36) (intraventricular injection; 25-3000 pmol) produces a dose-dependent increase (up to 14%; ED 50 value of 0.3 nmol for overall effects and 0.97 nmol for the peak effects) in mean arterial blood pressure in the awake, unrestrained male rat without affecting heart rate. Central administration of porcine Neuropeptide Y (13-36) produces marked vasodepressor and bradycardic actions in the anaesthetized α-chloralose and in the awake unrestrained male rat. Neuropeptide Y (13-36) (intracerebroventricular injection; 50 ng; alone; injected 30 and 15 min before measurements) injected into naïve mice impairs social novelty preference, but not sociability, and this effect is inhibited by the NPY Y 2 receptor antagonist BIIE 0246. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male ICR mice (age 4-7 weeks)Dosage: 50 ng/mouse Administration: Intracerebroventricular injection Result: Significantly decreased interaction time with the new stranger mouse in session 3 that NPY 13-36.Form:Solid... Read More | DescriptionPeptidoglycans are major components of bacterial cell walls, especially of gram-positve bacteria. Peptidoglycan are composed of alternating residues of β-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid and peptide chains that create cross-linkage to create mesh structures. DescriptionPeptidoglycans are major components of bacterial cell walls, especially of gram-positve bacteria. Peptidoglycan are composed of alternating residues of β-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid and peptide chains that create cross-linkage to create mesh structures. Peptidoglycans from different bacterial species can be compared to determine structural and compositional differences/variations and phylogenetic evolution. Peptidoglycans from different species may be used to differentiate and characterize peptidoglycan hydrolases... Read More | Protein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC 50 s of 136 and 74 nM for HIPK1 and HIPK2, and a K d of 9.5 nM for HIPK2.In VitroProtein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC 50 s of 136 and 74 nM for HIPK1 and HIPK2, and a K d of 9.5 nM Protein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC 50 s of 136 and 74 nM for HIPK1 and HIPK2, and a K d of 9.5 nM for HIPK2.In VitroProtein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC 50 s of 136 and 74 nM for HIPK1 and HIPK2, and a K d of 9.5 nM for HIPK2. Protein kinase inhibitor 1 (Compound A64) is not an effective Cdk1 inhibitor (IC 50 > 10 µM). A64 is moderately selective across a panel of kinases, with K d s of 3.7 nM (PIM3), 6.1 nM (CSNK2A2), 6.1 nM (CSNK2A2), 8.8 nM (DYRK1A), 9.5 nM (DAPK1), 31 nM (CSNK2A1), 37 nM (PIM1), 130 nM (DRAK2), 150 nM (CLK2), 190 nM (DRAK1), 220 nM (ULK2), 240 nM (CLK1), 250 nM (DYRK2), and 390 nM (ERK8) and IC 50 s of 19 nM (DYRK1A), 62 nM (DYRK1B), and 74 nM (HIPK2). MCE has not independently confirmed the accuracy of these methods. They are for reference only.IC50& Target:DYRK1 DYRK2... Read More |