| Description | Esterase, also known as carboxyl ester hydrolases, are a member of the hydrolytic enzyme superfamily. Esterase is widely present in organisms, such as helping to digest esters in food in the digestive system, and also participating in biological processes such as fatty acid metabolism within cells. Esterase, also known as carboxyl ester hydrolases, are a member of the hydrolytic enzyme superfamily. Esterase is widely present in organisms, such as helping to digest esters in food in the digestive system, and also participating in biological processes such as fatty acid metabolism within cells. Esterase is widely used in industry, such as in the production of biodiesel, food additives, and cosmetics. ≥15U /mg powder, ≥100 U/mg protein. Source: Porcine liver.Properties The molecular weight of esterase monomer is approximately 66kDa. It is a serine enzyme with two active sites on each molecule, which dissociates into active half molecules in the presence of dilute acid or concentrated saltStabilityEsterase acts on water-soluble carboxylic acid esters containing short chain fatty acids. Its function comes from the catalytic triad of Ser, His, and Asp/Glu, which is stable in the form of a triad under low temperature and low pH conditions.Application1、Used for kinetic resolution and asymmetric synthesis in organic chemistry.2、Used to reveal fluorescence in the UV visible spectrum.3、Used in pharmaceutical and industrial applications to catalyze the hydrolysis of pentaacetyl catechins and epicatechin.4、It is used to develop an alternative experimental scheme based on gel for screening bead binding catalytic activity in aqueous media.Attention1、 Avoid contact with skin and eyes.2、 For your safety and health, please wear Lab coat and disposable gloves... Read More | DescriptionApolipoprotein E (ApoE) is present in the brain and is mainly produced by astrocytes. It is a 299 amino acid glycoprotein of 34kDa. It is present in all classes of lipoproteins except LDL (low-density lipoprotein). APOE gene has three alleles, such as APOE ε3, APOE ε4and APOE &#DescriptionApolipoprotein E (ApoE) is present in the brain and is mainly produced by astrocytes. It is a 299 amino acid glycoprotein of 34kDa. It is present in all classes of lipoproteins except LDL (low-density lipoprotein). APOE gene has three alleles, such as APOE ε3, APOE ε4and APOE ε2. It is located on human chromosome 19q13.Preparation instructionsFormLyophillized from a 0.2 µm filtered solution in 20 mM sodium phosphate, pH 7.8.Principle... Read More | Inquire | Purity>97% SDS-PAGE.FunctionReceptor for interleukin-2 | Purity: >90%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description：KGF (keratinocyte growth factor), also known as FGF-7 (fibroblast growth factor-7), is one of 22 known members of the mouse FGF family of secreted proteins that plays a key role in development, Purity: >90%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description：KGF (keratinocyte growth factor), also known as FGF-7 (fibroblast growth factor-7), is one of 22 known members of the mouse FGF family of secreted proteins that plays a key role in development, morphogenesis, angiogenesis, wound healing, and tumorigenesis (1-4). KGF expression is restricted to cells of mesenchymal origin. When secreted, it acts as a paracrine growth factor for nearby epithelial cells (1). KGF speeds wound healing by being dramatically upregulated in response to damage to skin or internal structures that results in high local concentrations of inflammatory mediators such as IL-1 and TNF-alpha. (2, 5). KGF promotes cell migration and invasion, and mediates melanocyte transfer to keratinocytes upon UVB radiation (6, 7). It has been used ectopically to avoid chemotherapy-induced oral mucositis in patients with hematological malignancies (1). Deletion of KGF affects kidney development, producing abnormally small ureteric buds and fewer nephrons (8). It also impedes hair follicle differentiation (9). The 194 amino acid (aa) KGF precursor contains a 31 aa signal sequence and, like all other FGFs, an ~120 aa beta -trefoil scaffold that includes receptor- and heparin-binding sites. KGF signals only through the IIIb splice form of the tyrosine kinase receptor, FGF R2 (FGF R2-IIIb/KGF R) (10). Receptor dimerization requires an octameric or larger heparin or heparin sulfate proteoglycan (11). FGF-10, also called KGF2, shares 51% aa identity and similar function to KGF, but shows more limited expression than KGF and uses an additional receptor, FGF R2-IIIc (12). Following receptor engagement, KGF is typically degraded, while FGF-10 is recycled (12). Mature human KGF, which is active across species, shares 98% aa sequence identity with bovine, equine, ovine and canine, 96% with mouse and porcine, and 92% with rat KGF, respectively... Read More |