| Description | Storage buffer solution: Ultrapure waterProduct Introduction:This GTP (100mM, Tris Buffered) is provided in the form of a 100mM aqueous solution, titrated with Tris base to pH 7.0-7.5, and tested to be free of Nuclease, i.e. DNase and RNase. This product is suitable for routine molecular biology andStorage buffer solution: Ultrapure waterProduct Introduction:This GTP (100mM, Tris Buffered) is provided in the form of a 100mM aqueous solution, titrated with Tris base to pH 7.0-7.5, and tested to be free of Nuclease, i.e. DNase and RNase. This product is suitable for routine molecular biology and biochemical applications, such as in vitro transcription of SP6, T3, and T7 RNA polymerases to produce RNA, or for in vitro transcription of RNA, as well as RNA synthesis and amplification.matters needing attention:It can dissolve at room temperature and should be stored in an ice box or on an ice bath after dissolution. After use, it should be immediately stored at -20 ℃. Long term (infrequent use; 1-2 times a month) storage at -70 ℃. This product is only for scientific research by professionals and should not be used for clinical diagnosis or treatment, food or medicine, or stored in ordinary residential areas. For your safety and health, please wear lab coats and disposable gloves when operating... Read More | Inquire | 4-Methylumbelliferyl α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase. This is found in cell lysosomes, which is involved in the degradation of glycosaminoglycans. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent 4-Methylumbelliferyl α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase. This is found in cell lysosomes, which is involved in the degradation of glycosaminoglycans. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). This 4-Methylumbelliferyl α-L-iduronide form is the free acid, which offers a considerable weight for weight advantage over the 4-MU iduronide salt in terms of its application dose.:For further studies, use α-L-iduronidase gene silencing:siRNA and shRNA:reagents and α-L-iduronidase gene editing:CRISPR:knockout and activation products... Read More | IRAK-4 protein kinase inhibitor 2 (compound 1) is a potent inhibitor of interleukin-1 (IL-1) receptor-associated kinase-4 (IRAK-4), with an IC 50 of 4 µM. IRAK-4 protein kinase inhibitor 2 can be used for the research of inflammatory and immune-related conditions or disordersIn VitroIRAK-4 IRAK-4 protein kinase inhibitor 2 (compound 1) is a potent inhibitor of interleukin-1 (IL-1) receptor-associated kinase-4 (IRAK-4), with an IC 50 of 4 µM. IRAK-4 protein kinase inhibitor 2 can be used for the research of inflammatory and immune-related conditions or disordersIn VitroIRAK-4 protein kinase inhibitor 2 (compound 1) also inhibits IRAK-1, with an IC 50 of <10 µM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IRAK4 4 µM (IC 50 )... Read More | Inquire |