| Description | Clindamycin hydrochloride (neutralizer) is a water-soluble protein using a recombinant gene and is a dark brown liquid. A recombinant gene protein based on the chemical structure of clindamycin hydrochloride. The active center of its gene fragment can destroy the chemical structure formula of Clindamycin hydrochloride (neutralizer) is a water-soluble protein using a recombinant gene and is a dark brown liquid. A recombinant gene protein based on the chemical structure of clindamycin hydrochloride. The active center of its gene fragment can destroy the chemical structure formula of clindamycin hydrochloride and lose the antimicrobial properties of the drug after ring-opening/chain breaking.When doing sterility check of antibiotics, use a manual syringe to absorb sterile water and inject it into the drug vial, shake well, dissolve, and then suck it out. Add to 500ml solution of 0.9% sodium chloride, shake well, do not dissolve with the needle on the incubator, input, avoid high concentration of solution through the filter membrane, resulting in difficult to rinse thoroughly.Here, it is emphasized again: when doing sterile examination of antibiotics, it is necessary to inject sterile water into the manual syringe to dissolve the sample, and then transfer the dissolved sample to 500ml solution of 0.9% sodium chloride, so that the sample will not cause local concentration too high, difficult to wash thoroughly through the filter membrane.During sterility test, take 3ml of enzyme and add 2ml of sterile water and shake well to make a diluent of Clindamycin hydrochloride (neutralizer). Take 2ml of enzyme diluent and add 1500ml of rinsing solution and shake well. After the rinse solution has washed the filter membrane of the incubator, the pump is exhausted. Use a manual syringe to Pierce the respiratory mouth of the three incubators, add 1ml of diluting enzyme, spread the enzyme on the entire surface of the filter membrane as much as possible, rest for 10 minutes, and make the high concentration of enzyme fully contact with the filter membrane of the incubator, so as to destroy (neutralize and inactivate) the residual clindamycin hydrochloride drug on the filter membrane, and then pump into the corresponding medium and shake well. Positive pairs were treated with 1ml of E. coli (100CFU/ml).Adding 2ml dilution of clindamycin hydrochloride (neutralizer) to the rinse solution can remove a small amount of antimicrobial properties of clindamycin hydrochloride remaining in the filter membrane.Adding 1ml dilution of clindamycin hydrochloride (neutralizer) to three incubators can remove a small amount of antimicrobial activity of clindamycin hydrochloride remaining on the inner walls of the incubators and on the surface of the filter membrane.Shake the positive pair gently once a day in the morning and afternoon.Customers can do methodological verification according to the above, but also according to the actual operation of the verification... Read More | Inquire | Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description：CD200 R1, also known as OX-2 receptor, is a 90 kDa transmembrane protein in the immunoglobulin superfamily and is important in the regulation of myeloid cell activity. The human CD200 R1 cDNA encodes a 325 Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description：CD200 R1, also known as OX-2 receptor, is a 90 kDa transmembrane protein in the immunoglobulin superfamily and is important in the regulation of myeloid cell activity. The human CD200 R1 cDNA encodes a 325 amino acid (aa) precursor that includes a 28 aa signal sequence, a 215 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 61 aa cytoplasmic domain. The ECD is composed of one Ig-like V-type domain and one Ig-like C2-type domain. Within the ECD, human CD200 R1 shares 56% aa sequence identity with both mouse and rat CD200 R1. Alternate splicing of the human CD200 R1 mRNA generates four isoforms, two of which are truncated in the Ig-C2 domain and are likely secreted. In human, a separate CD200 RL gene encodes a protein that shares 81% ECD aa identity with CD200 R1. In mouse, at least four genes for CD200 R1-like molecules have been described. CD200 R1 expression is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, while its ligand, CD200, is widely distributed. Disruption of this receptor-ligand system by knockout of the CD200 gene in mice leads to increased macrophage number and activation and predisposition to autoimmune disorders. Association of CD200 with CD200 R1 takes place between their respective N-terminal Ig-like domains. The capacity of CD200 R1-like molecules to interact with CD200 is controversial. CD200 R1 propagates inhibitory signals despite lacking a cytoplasmic ITIM (immunoreceptor tyrosine-based inhibitory motif). CD200 R1-like molecules, in contrast, are potentially activating receptors by means of their association with DAP12. CD200R1 signaling inhibits the expression of proinflammatory molecules including TNFs, IFNs, and inducible nitric oxide synthase in response to selected stimuli, which implicate that CD200/CD200R1 inhibitory signaling pathway plays a prominent role in limiting inflammation in a wide range of inflammatory diseases. Furthermore, the CD200/CD200R inhibitory signaling constitutes one of the most suitable endogenous immunoregulatory molecule candidate to restore the immune suppressive status of the CNS altered in chronic neuroinflammatory situations... Read More | Purity>95% as determined by SDS-PAGE and Coomassie blue stainingFunctionThe heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro.Sequence Purity>95% as determined by SDS-PAGE and Coomassie blue stainingFunctionThe heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro.Sequence similaritiesBelongs to the heparin-binding growth factors family.Cellular localizationSecreted. Cytoplasm. Cytoplasm > cell cortex. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1... Read More | Purity> 97% (SDS-PAGE&HPLC)Endotoxin level<0.1 EU/µgFunctionProduced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase |