| Description | Buy Purified Native Human Apolipoprotein A4 (ApoA4), Human Plasma.Bulk Qty Available.Apolipoprotein AIV (Apo AIV), is a major component of HDL and chylomicrons, is actively synthesized in the small intestine during fat absorption and incorporated onto the surface of nascent chylomicrons that are Buy Purified Native Human Apolipoprotein A4 (ApoA4), Human Plasma.Bulk Qty Available.Apolipoprotein AIV (Apo AIV), is a major component of HDL and chylomicrons, is actively synthesized in the small intestine during fat absorption and incorporated onto the surface of nascent chylomicrons that are then secreted into lymph. When these chylomicrons enter plasma, Apo-AIV dissociates from the surface and is found primarily in the lipoprotein-free fraction.Apo AIV may play a role in the secretion and catabolism of chylomicrons and VLDL. It is required for efficient activation of lipoprotein lipase by ApoC-II and is a potent activator of LCAT. Apo AIV is an amphipathic protein that can emulsify lipids and has been linked to protective roles against cardiovascular disease and obesity.Ref: Weinburg, R.B. and Scanu, A. M. J Lipid Res 1983. 24, 52. Dieplinger, H. Menzel, H-J., and Utermann, G. 1992. Lipoprotein Analysis A Practical Approach. (CA Converse and ER Skinner, eds), 43. Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests... Read More | Amine-Reactive probe which passively diffuse into cells and it is nonfluorescent until the acetate groups are cleaved by intracellular esterases to yield the highly fluorescent, amine-reactive fluorophore. Upon reaction with amine-containing residues of intracellular proteins, these probes form dye Amine-Reactive probe which passively diffuse into cells and it is nonfluorescent until the acetate groups are cleaved by intracellular esterases to yield the highly fluorescent, amine-reactive fluorophore. Upon reaction with amine-containing residues of intracellular proteins, these probes form dye protein adducts that are well retained in cells as they move and divide during embryonic development.A Non-fluorescent cell permeant amine-reactive probe for long term tracing of cell... Read More | Inquire | IRE1α kinase-IN-2 is a potent IRE1α kinase inhibitor, with an EC 50 of 0.82 µM. IRE1α kinase-IN-2 inhibits IRE1α kinase autophosphorylation (IC 50 =3.12 µM). IRE1α kinase-IN-2 inhibits XBP1 mRNA splicing in the WT cell lines.In VitroIRE1α kinase-IN-2 (compoundIRE1α kinase-IN-2 is a potent IRE1α kinase inhibitor, with an EC 50 of 0.82 µM. IRE1α kinase-IN-2 inhibits IRE1α kinase autophosphorylation (IC 50 =3.12 µM). IRE1α kinase-IN-2 inhibits XBP1 mRNA splicing in the WT cell lines.In VitroIRE1α kinase-IN-2 (compound 3) inhibits XBP1 mRNA splicing, even during ER stress. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid... Read More | Protein:BovineEnzyme:Horseradish peroxidase |