| Description | 75% of Apo A in HDL is Apo AI. Levels of Apo AI are inversely related to the risk of coronary heart disease. Apo AI is also thought to activate LCAT (lecithin cholesterol acyl tranferase). In normal plasma, Apo AI levels range from 90-130 mg per 100 ml.Prepared from fresh, non-frozen plasma shown to75% of Apo A in HDL is Apo AI. Levels of Apo AI are inversely related to the risk of coronary heart disease. Apo AI is also thought to activate LCAT (lecithin cholesterol acyl tranferase). In normal plasma, Apo AI levels range from 90-130 mg per 100 ml.Prepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.Aladdin products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.
Buy Purified Native Human Apolipoprotein AI (ApoA1), Human Plasma.Bulk Qty Available.75% of Apo A in HDL is Apo AI. Levels of Apo AI are inversely related to the risk of coronary heart disease. Apo AI is also thought to activate LCAT (lecithin cholesterol acyl tranferase). In normal plasma, Apo AI levels range from 90-130 mg per 100 ml. Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.Product Citation:Soffientini, Ugo, et al. "Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: Implications for diabetic dyslipidaemia and steatosis." Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids 1841.10 (2014): 1372-1382.Soffientini U, Dolan S, Graham A.Cytosolic lipid trafficking proteins STARD4 and STARD5 modulate hepatic neutral lipid metabolism: implications for diabetic dyslipidaemia and steatosis.Journal of Diabetes and Metabolism, Volume 6, Issue number 588. DOI: 10.4172/2155-6156.1000558.Winford, Sidney, Moriah Tobin, and Eitan Gross. "Surface-induced assembly of apolipoprotein AI: Implications for symmetry-driven non-cooperative clustering."Journal of Crystal Growth 343, no. 1 (2012): 38-44.Konno, Shunichi, Masami Tanio, Itsuko Ishii, Kazuhiko Machida, Fumiaki Matsumoto, Kaneshige Satoh, Masayuki Aso, and Yasushi Saito. "Ceiling culture-derived proliferative adipocytes are a possible delivery vehicle for enzyme replacement therapy in lecithin: cholesterol acyltransferase deficiency." Open Gene Therapy Journal 4 (2011): 1-10.Scharadin TM, et al.Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system.PLOS One, 2017 Jun 6;12(6).Prathipati P, Zhu J, Dong X.Development of novel HDL-mimicking α-tocopherol-coated nanoparticles to encapsulate nerve growth factor and evaluation of biodistribution.Eur J Pharm Biopharm. 2016 Nov;108:126-135. doi: 10.1016/j.ejpb.2016.08.005. Epub 2016 Aug 12... Read More | HIV-1 Tat Protein Peptide is a synthetic peptide that includes the sequence responsible for the cellular uptake of the human immunodeficiency virus-1 Tat protein, consisting of the polycationic region 49-57. The peptide is part of the protein transduction domain (PTD) and was shown to enable the HIV-1 Tat Protein Peptide is a synthetic peptide that includes the sequence responsible for the cellular uptake of the human immunodeficiency virus-1 Tat protein, consisting of the polycationic region 49-57. The peptide is part of the protein transduction domain (PTD) and was shown to enable the introduction of nucleic acids into cells... Read More | Apatinib(YN-968D1) is an orally bioavailable, selective VEGFR2 inhibitor with IC50 of 1 nM | Purity: >90%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: Major histocompatibility complex, class II, DR alpha (HLA-DRA) belongs to the MHC class II family. HLA-DRA binds peptides derived from antigens which access the endocytic route of antigen presenting cells (APC) Purity: >90%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: Major histocompatibility complex, class II, DR alpha (HLA-DRA) belongs to the MHC class II family. HLA-DRA binds peptides derived from antigens which access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for identification by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mainly by degradation of proteins which access the endocytic route, where they are processed by lysosomal proteases and other hydrolases... Read More | Purity: >90%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description：KGF (keratinocyte growth factor), also known as FGF-7 (fibroblast growth factor-7), is one of 22 known members of the mouse FGF family of secreted proteins that plays a key role in development, Purity: >90%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description：KGF (keratinocyte growth factor), also known as FGF-7 (fibroblast growth factor-7), is one of 22 known members of the mouse FGF family of secreted proteins that plays a key role in development, morphogenesis, angiogenesis, wound healing, and tumorigenesis (1-4). KGF expression is restricted to cells of mesenchymal origin. When secreted, it acts as a paracrine growth factor for nearby epithelial cells (1). KGF speeds wound healing by being dramatically upregulated in response to damage to skin or internal structures that results in high local concentrations of inflammatory mediators such as IL-1 and TNF-alpha. (2, 5). KGF promotes cell migration and invasion, and mediates melanocyte transfer to keratinocytes upon UVB radiation (6, 7). It has been used ectopically to avoid chemotherapy-induced oral mucositis in patients with hematological malignancies (1). Deletion of KGF affects kidney development, producing abnormally small ureteric buds and fewer nephrons (8). It also impedes hair follicle differentiation (9). The 194 amino acid (aa) KGF precursor contains a 31 aa signal sequence and, like all other FGFs, an ~120 aa beta -trefoil scaffold that includes receptor- and heparin-binding sites. KGF signals only through the IIIb splice form of the tyrosine kinase receptor, FGF R2 (FGF R2-IIIb/KGF R) (10). Receptor dimerization requires an octameric or larger heparin or heparin sulfate proteoglycan (11). FGF-10, also called KGF2, shares 51% aa identity and similar function to KGF, but shows more limited expression than KGF and uses an additional receptor, FGF R2-IIIc (12). Following receptor engagement, KGF is typically degraded, while FGF-10 is recycled (12). Mature human KGF, which is active across species, shares 98% aa sequence identity with bovine, equine, ovine and canine, 96% with mouse and porcine, and 92% with rat KGF, respectively... Read More |