| Description | LYPD3 Human Pre-designed siRNA Set A contains three designed siRNAs for LYPD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Components LYPD3 siRNA-1: 5 nmol (HPLC) LYPD3 siRNA-2: 5 nmol (HPLC) LYPD3 siRNA-3: 5 nmol (HPLC) siRNA Negative Control:LYPD3 Human Pre-designed siRNA Set A contains three designed siRNAs for LYPD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Components LYPD3 siRNA-1: 5 nmol (HPLC) LYPD3 siRNA-2: 5 nmol (HPLC) LYPD3 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 nmol (HPLC) FAM-labeled siRNA Negative Control: 5 nmol (HPLC) GAPDH siRNA Positive Control:5 nmol (HPLC)... Read More | The Leuconostoc GPDH exhibits dual coenzyme specificity, namely NAD and NADP (Olive and Levy, Biochem., 6, 730 730, 1967). When assayed under conditions that are optimal for the particular coenzyme, the ratio of observed catalytic activity is NAD/NADP = 1.8 | IRE1α kinase-IN-2 is a potent IRE1α kinase inhibitor, with an EC 50 of 0.82 µM. IRE1α kinase-IN-2 inhibits IRE1α kinase autophosphorylation (IC 50 =3.12 µM). IRE1α kinase-IN-2 inhibits XBP1 mRNA splicing in the WT cell lines.In VitroIRE1α kinase-IN-2 (compoundIRE1α kinase-IN-2 is a potent IRE1α kinase inhibitor, with an EC 50 of 0.82 µM. IRE1α kinase-IN-2 inhibits IRE1α kinase autophosphorylation (IC 50 =3.12 µM). IRE1α kinase-IN-2 inhibits XBP1 mRNA splicing in the WT cell lines.In VitroIRE1α kinase-IN-2 (compound 3) inhibits XBP1 mRNA splicing, even during ER stress. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid... Read More | Biochemical Test:Electrophoresis (purity > 80%) | Format:1-ComponentEnzyme:Horseradish peroxidase |