| Type | Bioactive Small Molecules | Chelating Agents & Ligands | Dyes, Stains, & Indicators | Chelating Agents & Ligands | Antibodies |
| Description | Casp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Casp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Components Casp1 siRNA-1: 5 nmol (HPLC) Casp1 siRNA-2: 5 nmol (HPLC) Casp1 siRNA-3: 5 nmol (HPLC) siRNA Negative Control:Casp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Casp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Components Casp1 siRNA-1: 5 nmol (HPLC) Casp1 siRNA-2: 5 nmol (HPLC) Casp1 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 nmol (HPLC) FAM-labeled siRNA Negative Control: 5 nmol (HPLC) GAPDH siRNA Positive Control:5 nmol (HPLC)... Read More | Inquire | Amine-Reactive probe which passively diffuse into cells and it is nonfluorescent until the acetate groups are cleaved by intracellular esterases to yield the highly fluorescent, amine-reactive fluorophore. Upon reaction with amine-containing residues of intracellular proteins, these probes form dye Amine-Reactive probe which passively diffuse into cells and it is nonfluorescent until the acetate groups are cleaved by intracellular esterases to yield the highly fluorescent, amine-reactive fluorophore. Upon reaction with amine-containing residues of intracellular proteins, these probes form dye protein adducts that are well retained in cells as they move and divide during embryonic development.A Non-fluorescent cell permeant amine-reactive probe for long term tracing of cell... Read More | IRE1α kinase-IN-2 is a potent IRE1α kinase inhibitor, with an EC 50 of 0.82 µM. IRE1α kinase-IN-2 inhibits IRE1α kinase autophosphorylation (IC 50 =3.12 µM). IRE1α kinase-IN-2 inhibits XBP1 mRNA splicing in the WT cell lines.In VitroIRE1α kinase-IN-2 (compoundIRE1α kinase-IN-2 is a potent IRE1α kinase inhibitor, with an EC 50 of 0.82 µM. IRE1α kinase-IN-2 inhibits IRE1α kinase autophosphorylation (IC 50 =3.12 µM). IRE1α kinase-IN-2 inhibits XBP1 mRNA splicing in the WT cell lines.In VitroIRE1α kinase-IN-2 (compound 3) inhibits XBP1 mRNA splicing, even during ER stress. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid... Read More | Biochemical Test:SDS-PAGE (purity > 80%); Western blot with patient sample.Calculated Isoelectric Point:pH 5.68 |