| Description | ERI3 Human Pre-designed siRNA Set A contains three designed siRNAs for ERI3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Components ERI3 siRNA-1: 5 nmol (HPLC) ERI3 siRNA-2: 5 nmol (HPLC) ERI3 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 ERI3 Human Pre-designed siRNA Set A contains three designed siRNAs for ERI3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Components ERI3 siRNA-1: 5 nmol (HPLC) ERI3 siRNA-2: 5 nmol (HPLC) ERI3 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 nmol (HPLC) FAM-labeled siRNA Negative Control: 5 nmol (HPLC) GAPDH siRNA Positive Control:5 nmol (HPLC)... Read More | Inquire | Inquire | Purity>95% as determined by SDS-PAGE and Coomassie blue stainingFunctionThe heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro.Sequence Purity>95% as determined by SDS-PAGE and Coomassie blue stainingFunctionThe heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro.Sequence similaritiesBelongs to the heparin-binding growth factors family.Cellular localizationSecreted. Cytoplasm. Cytoplasm > cell cortex. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1... Read More | Purity>95% (SDS-PAGE) Endotoxin level<1.0 EU/µgFunctionInhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells |