| Description | Ackr3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ackr3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control. Components Ackr3 siRNA-1: 5 nmol (HPLC) Ackr3 siRNA-2: 5 nmol (HPLC) Ackr3 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 Ackr3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ackr3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control. Components Ackr3 siRNA-1: 5 nmol (HPLC) Ackr3 siRNA-2: 5 nmol (HPLC) Ackr3 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 nmol (HPLC) FAM-labeled siRNA Negative Control: 5 nmol (HPLC) GAPDH siRNA Positive Control:5 nmol (HPLC)... Read More | DescriptionApolipoprotein E (ApoE) is present in the brain and is mainly produced by astrocytes. It is a 299 amino acid glycoprotein of 34kDa. It is present in all classes of lipoproteins except LDL (low-density lipoprotein). APOE gene has three alleles, such as APOE ε3, APOE ε4and APOE DescriptionApolipoprotein E (ApoE) is present in the brain and is mainly produced by astrocytes. It is a 299 amino acid glycoprotein of 34kDa. It is present in all classes of lipoproteins except LDL (low-density lipoprotein). APOE gene has three alleles, such as APOE ε3, APOE ε4and APOE ε2. It is located on human chromosome 19q13.Preparation instructionsFormLyophillized from a 0.2 µm filtered solution in 20 mM sodium phosphate, pH 7.8.Principle... Read More | Purity>95% SDS-PAGEFunctionHas hepatocyte mitogenic activity | Purity>95% (SDS-PAGE) Endotoxin level<1.0 EU/µgFunctionMay play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis | Purity> 97 % by SDS-PAGE and HPLC analyses.FunctionReceptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation whichPurity> 97 % by SDS-PAGE and HPLC analyses.FunctionReceptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase... Read More |