| Description | Comt Mouse Pre-designed siRNA Set A contains three designed siRNAs for Comt gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Components Comt siRNA-1: 5 nmol (HPLC) Comt siRNA-2: 5 nmol (HPLC) Comt siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 Comt Mouse Pre-designed siRNA Set A contains three designed siRNAs for Comt gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Components Comt siRNA-1: 5 nmol (HPLC) Comt siRNA-2: 5 nmol (HPLC) Comt siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 nmol (HPLC) FAM-labeled siRNA Negative Control: 5 nmol (HPLC) GAPDH siRNA Positive Control:5 nmol (HPLC)... Read More | Biochemical Test:SDS-PAGE (purity > 80%); Western blot with patient sample.Calculated Isoelectric Point:pH 5.68 | p53 and MDM2 proteins-interaction-inhibitor (chiral) (Compound 32) is an inhibitor of the interaction between p53 and MDM2 proteins | Inquire | FunctionSignal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not FunctionSignal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development (By similarity). The type I OSM receptor is capable of transducing OSM-specific signaling events.Post-translationalPhosphorylation of Ser-782 down-regulates cell surface expression. Heavily N-glycosylated... Read More |