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| Company | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation |
| Item | ANO6 Human Pre-designed siRNA Set A | G-Protein antagonist peptide TFA | HIV-1 matrix protein p17 | Recombinant Human GDF6 Protein | SHP2 protein degrader-2 |
| Catalog Number | A1479408 | G409316 | rp174222 | rp146383 | S648891 |
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| Quantity | 1Set | 50mg, 10mg, 100mg, 5mg, 25mg, 1mg | 500µg, 1mg | 100µg, 10µg, 50µg, 1mg | 50mg, 10mg, 100mg, 5mg, 25mg, 1mg |
| Type | Bioactive Small Molecules | Chelating Agents & Ligands | Chelating Agents & Ligands | Proteins | Chelating Agents & Ligands |
| Description | ANO6 Human Pre-designed siRNA Set A contains three designed siRNAs for ANO6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Components ANO6 siRNA-1: 5 nmol (HPLC) ANO6 siRNA-2: 5 nmol (HPLC) ANO6 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 ANO6 Human Pre-designed siRNA Set A contains three designed siRNAs for ANO6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Components ANO6 siRNA-1: 5 nmol (HPLC) ANO6 siRNA-2: 5 nmol (HPLC) ANO6 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 nmol (HPLC) FAM-labeled siRNA Negative Control: 5 nmol (HPLC) GAPDH siRNA Positive Control:5 nmol (HPLC)... Read More | Inquire | Inquire | Purity> 95% by SDS-PAGE and HPLC analyses.FunctionGrowth factor that controls proliferation and cellular differentiation in the retina and bone formation. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and Purity> 95% by SDS-PAGE and HPLC analyses.FunctionGrowth factor that controls proliferation and cellular differentiation in the retina and bone formation. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map (PubMed:23307924). Required for normal formation of bones and joints in the limbs, skull, digits and axial skeleton. Plays a key role in establishing boundaries between skeletal elements during development. Regulation of GDF6 expression seems to be a mechanism for evolving species-specific changes in skeletal strucutres. Seems to positively regulates differentiation of chondrogenic tissue through the growth factor receptors subunits BMPR1A, BMPR1B, BMPR2 and ACVR2A, leading to the activation of SMAD1-SMAD5-SMAD8 complex. The regulation of chondrogenic differentiation is inhibited by NOG (PubMed:26643732). Also involved in the induction of adipogenesis from mesenchymal stem cells. This mechanism acts through the growth factor receptors subunits BMPR1A, BMPR2 and ACVR2A and the activation of SMAD1-SMAD5-SMAD8 complex and MAPK14/p38... Read More | SHP2 protein degrader-2 (SHP2-D26) is a SHP2 protein PROTAC degrader. SHP2 protein degrader-2 reduces expression level of SHP2 in various cancer cells.In VitroSHP2 protein degrader-2 (SHP2-D26) achieves excellent degradation of SHP2 with the DC 50 (the concentration where 50% of the protein has beenSHP2 protein degrader-2 (SHP2-D26) is a SHP2 protein PROTAC degrader. SHP2 protein degrader-2 reduces expression level of SHP2 in various cancer cells.In VitroSHP2 protein degrader-2 (SHP2-D26) achieves excellent degradation of SHP2 with the DC 50 (the concentration where 50% of the protein has been degraded) values of 2.6 nM and 6.0 nM for MV4;11 and KYSE520 cells, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid... Read More |
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