| Description | ANO6 Human Pre-designed siRNA Set A contains three designed siRNAs for ANO6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Components ANO6 siRNA-1: 5 nmol (HPLC) ANO6 siRNA-2: 5 nmol (HPLC) ANO6 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 ANO6 Human Pre-designed siRNA Set A contains three designed siRNAs for ANO6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Components ANO6 siRNA-1: 5 nmol (HPLC) ANO6 siRNA-2: 5 nmol (HPLC) ANO6 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 nmol (HPLC) FAM-labeled siRNA Negative Control: 5 nmol (HPLC) GAPDH siRNA Positive Control:5 nmol (HPLC)... Read More | Sequence:Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-AlaBiochemical mechanism:Amyloid protein β Protein segment 1-42 (A β 1-42) It has antioxidant and neuroprotective Sequence:Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-AlaBiochemical mechanism:Amyloid protein β Protein segment 1-42 (A β 1-42) It has antioxidant and neuroprotective properties. Amyloid protein β Protein accumulation is associated with Alzheimer's disease (AD) and Down syndrome. A β 1-42 regulates cholesterol transport and acts as a transcription factor. It may also have anti-inflammatory and antimicrobial effects.Application:Amyloid protein is found in the brain of patients with Alzheimer's disease and Down syndrome β- The main segment of the protein.Amyloid protein β Protein fragments 1-42 have been used to:1. A β Preparation of 1-42 oligomer2. Western blot analysis3. Immunomagnetic Reduction (IMR) Plasma A β 42 Detected interference test4. Study the effect of resveratrol on A β 1-42 induced impairment of spatial learning, memory and synaptic plasticity5. Study A β Role in epithelial cell culture... Read More | Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description：HSPD1, also known as HSP60, is a member of the chaperonin family. HSPD1 may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description：HSPD1, also known as HSP60, is a member of the chaperonin family. HSPD1 may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. It may also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. HSPD1 gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. Defects in HSPD1 are a cause of spastic paraplegia autosomal dominant type 13 (SPG13). Spastic paraplegia is a degenerative spinal cord disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Defects in HSPD1 are the cause of leukodystrophy hypomyelinating type 4 (HLD4); also called mitochondrial HSP60 chaperonopathy or MitCHAP-60 disease. HLD4 is a severe autosomal recessive hypomyelinating leukodystrophy. HSPD1 is clinically characterized by infantile-onset rotary nystagmus, progressive spastic paraplegia, neurologic regression, motor impairment, profound mental retardation. Death usually occurs within the first two decades of life... Read More | Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma. KLK3, also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases. KLK3 contains one peptidase S1 domain. KLK3 is a glycoprotein produced almost exclusively by the prostate gland. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers... Read More | Inquire |