| Description | DNA Methylation Magnetic Beads are magnetic solid-phase carriers specifically designed for DNA methylation processing workflows. Utilizing a specialized manufacturing process, these beads exhibit high specificity, large surface area, and strong magnetic properties, combined with exceptional DNA Methylation Magnetic Beads are magnetic solid-phase carriers specifically designed for DNA methylation processing workflows. Utilizing a specialized manufacturing process, these beads exhibit high specificity, large surface area, and strong magnetic properties, combined with exceptional hydrophilicity and nucleic acid capture capacity.This product demonstrates excellent extraction efficiency for bisulfite-treated DNA (e.g., via sodium bisulfite conversion) and is compatible with automated liquid-phase nucleic acid extraction platforms. It is widely used in life science research and applications involving epigenetic studies.Key Features✔ Excellent handling performance.✔ High specificity for bisulfite-converted DNA.✔ Superior reproducibility.ProtocolAdd an appropriate volume of magnetic beads and binding buffer to bisulfite-treated DNA samples.Incubate to allow nucleic acid binding.Separate bead-bound nucleic acids from unbound materials using magnetic separation.Wash beads with wash buffer to remove impurities; retain beads using a magnet.Elute nucleic acids with elution buffer; separate beads from the final product magnetically.PrecautionsAvoid freezing, drying, or centrifugation – these may cause bead aggregation and affect resuspension.Vortex thoroughly before use to ensure a homogeneous suspension.Storage:Stable for 2 years at 2–8°C.Slight color variations under normal storage conditions do not affect performance... Read More | Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description:GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase) is a Protein Coding gene. Diseases associated with GAPDH include Microcephaly 21, Primary, Autosomal Recessive and Schistosomiasis. Among its related pathways are Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description:GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase) is a Protein Coding gene. Diseases associated with GAPDH include Microcephaly 21, Primary, Autosomal Recessive and Schistosomiasis. Among its related pathways are glycolysis (BioCyc) and gluconeogenesis III. Gene Ontology (GO) annotations related to this gene include identical protein binding and NAD binding. An important paralog of this gene is GAPDHS... Read More | Inquire | Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description:Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description:Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation... Read More | Purity>98% by SDS-PAGE and HPLC analyses.FunctionAppears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic Purity>98% by SDS-PAGE and HPLC analyses.FunctionAppears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca (2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity... Read More |