| Description | Grm8 Rat Pre-designed siRNA Set A contains three designed siRNAs for Grm8 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control. Components Grm8 siRNA-1: 5 nmol (HPLC) Grm8 siRNA-2: 5 nmol (HPLC) Grm8 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 nmol (Grm8 Rat Pre-designed siRNA Set A contains three designed siRNAs for Grm8 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control. Components Grm8 siRNA-1: 5 nmol (HPLC) Grm8 siRNA-2: 5 nmol (HPLC) Grm8 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 nmol (HPLC) FAM-labeled siRNA Negative Control: 5 nmol (HPLC) GAPDH siRNA Positive Control:5 nmol (HPLC)... Read More | Inquire | 4-Methylumbelliferyl α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase. This is found in cell lysosomes, which is involved in the degradation of glycosaminoglycans. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent 4-Methylumbelliferyl α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase. This is found in cell lysosomes, which is involved in the degradation of glycosaminoglycans. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). This 4-Methylumbelliferyl α-L-iduronide form is the free acid, which offers a considerable weight for weight advantage over the 4-MU iduronide salt in terms of its application dose.:For further studies, use α-L-iduronidase gene silencing:siRNA and shRNA:reagents and α-L-iduronidase gene editing:CRISPR:knockout and activation products... Read More | Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months | Purity>95% (SDS-PAGE) Endotoxin level<1.0 EU/µgFunctionInhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells |