| Description | CLEC4F Human Pre-designed siRNA Set A contains three designed siRNAs for CLEC4F gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Components CLEC4F siRNA-1: 5 nmol (HPLC) CLEC4F siRNA-2: 5 nmol (HPLC) CLEC4F siRNA-3: 5 nmol (HPLC) siRNA Negative CLEC4F Human Pre-designed siRNA Set A contains three designed siRNAs for CLEC4F gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Components CLEC4F siRNA-1: 5 nmol (HPLC) CLEC4F siRNA-2: 5 nmol (HPLC) CLEC4F siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 nmol (HPLC) FAM-labeled siRNA Negative Control: 5 nmol (HPLC) GAPDH siRNA Positive Control:5 nmol (HPLC)... Read More | Biochemical Test:SDS-PAGE (purity > 80%); Western blot with patient sample.Calculated Isoelectric Point:pH 8.38 | Inquire | Purity>95% (SDS-PAGE) Endotoxin level<1.0 EU/µgFunctionInhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells | Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description:BIRC5, also known as Survivin and EPR-1, is a member of theIAP family. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but BIRC5 has only a single BIR domain. It is expressed cell Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description:BIRC5, also known as Survivin and EPR-1, is a member of theIAP family. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but BIRC5 has only a single BIR domain. It is expressed cell cycle-dependently and highly expressed at mitosis. As a multitasking protein, BIRC5 has dual roles in promoting cell proliferation and preventing apoptosis. Survivin is a component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Survivin acts as an important regulator of the localization of this complex. It may counteract a default induction of apoptosis in G2/M phase... Read More |