| Description | Ac-DMLD-CMK TFA is a polypeptide targeting the mouse caspase 3-Gsdme signaling pathway. Ac-DMLD-CMK TFA can specifically inhibit the activation of caspase 3 and Gsdme. Ac-DMLD-CMK TFA blocks the cleavage of Gsdme by caspase 3, inhibits the occurrence of pyroptosis, thereby reducing renal tubular Ac-DMLD-CMK TFA is a polypeptide targeting the mouse caspase 3-Gsdme signaling pathway. Ac-DMLD-CMK TFA can specifically inhibit the activation of caspase 3 and Gsdme. Ac-DMLD-CMK TFA blocks the cleavage of Gsdme by caspase 3, inhibits the occurrence of pyroptosis, thereby reducing renal tubular epithelial cell injury and the secretion of inflammatory cytokines. Ac-DMLD-CMK TFA reduces the levels of serum creatinine and blood urea nitrogen in mice induced by Cisplatin (HY-17394) and alleviates the deterioration of kidney function. Ac-DMLD-CMK TFA is promising for research of chemotherapy drug-induced nephrotoxicity[1]... Read More | Exoenzyme C3, clostridium botulinum, is a mono-ADP-ribosylating enzyme. Exoenzyme C3, clostridium botulinum specifically modifies RhoA, B, and C by transferring ADP-ribose to them, thereby inactivating these GTPases. Exoenzyme C3, clostridium botulinum can induce neuronal axonal and dendritic growthExoenzyme C3, clostridium botulinum, is a mono-ADP-ribosylating enzyme. Exoenzyme C3, clostridium botulinum specifically modifies RhoA, B, and C by transferring ADP-ribose to them, thereby inactivating these GTPases. Exoenzyme C3, clostridium botulinum can induce neuronal axonal and dendritic growth, inhibit macrophage migration, and regulate cytoskeletal dynamics. Exoenzyme C3, clostridium botulinum can be used in the research of spinal cord injury and diabetic painful neuropathy[1][2][3][4][5]... Read More | Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations | Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO−) in the vascular wall, contributing to the reduction of blood pressure[1][2][3]. This product is recombinant Human Serum Albumin expressed in a microbial expression system... Read More | Parathyroid hormone (1-34) (rat) (acetate) is a parathyroid hormone. Parathyroid hormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroid hormone (1-34) (rat) can be used for the research of osteoporosis[1][2] |