| Description | FPP29 is a novel, efficient, and safe peptide based FOXM1 PROTAC degrader. FPP29 significantly inhibits cell scratch healing, induces apoptosis, and suppresses clone formation. FPP29 has cytotoxicity (IC50 = 3.65 µM). FPP29 can be used for research on cancers such as liver cancer. (CPP: HY-FPP29 is a novel, efficient, and safe peptide based FOXM1 PROTAC degrader. FPP29 significantly inhibits cell scratch healing, induces apoptosis, and suppresses clone formation. FPP29 has cytotoxicity (IC50 = 3.65 µM). FPP29 can be used for research on cancers such as liver cancer. (CPP: HY-P0133, VHL Ligand: HY-P11493, Linker: HY-W013664, FOXM1 Ligand: HY-P11494)[1]... Read More | GIP (Gastric inhibitory polypeptide) (mouse) is a gastrointestinal hormone that is secreted by the intestinal K cells, and also expressed in and secreted from pancreatic islets. GIP (mouse) promotes insulin secretion from pancreatic β cells via the G-protein-coupled GIP receptor (GIPR). GIP (GIP (Gastric inhibitory polypeptide) (mouse) is a gastrointestinal hormone that is secreted by the intestinal K cells, and also expressed in and secreted from pancreatic islets. GIP (mouse) promotes insulin secretion from pancreatic β cells via the G-protein-coupled GIP receptor (GIPR). GIP (mouse) promotes pancreatic β cell proliferation and inhibits apoptosis. GIP (mouse) also exerts direct lipogenic effects on adipose tissue[1][2][3]... Read More | HEP-1 (Human ezrin peptide (324 - 337)) is an orally active peptide with antiviral, anti-inflammatory, and immunomodulatory activities. HEP-1 is effective against infections by various viruses such as HIV, HCV, herpes viruses, HPV, and influenza viruses. As an immunomodulator, HEP-1 can enhance the HEP-1 (Human ezrin peptide (324 - 337)) is an orally active peptide with antiviral, anti-inflammatory, and immunomodulatory activities. HEP-1 is effective against infections by various viruses such as HIV, HCV, herpes viruses, HPV, and influenza viruses. As an immunomodulator, HEP-1 can enhance the adaptive immunity mediated by B cells and T cells. HEP-1 can also increase the antibody titers after hepatitis B vaccination. HEP-1 can be used in the research of viral infections and inflammation-related diseases[1][2]... Read More | Lei-Dab7 TFA is a high affinity, selective KCa2.2 (SK2) channel blocker (Kd=3.8 nM). Lei-Dab7 TFA exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, Kv and Kir2.1. Lei-Dab7 TFA increases theta-burst responses and increases LTP in rat hippocampal slices in vitro | Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4) |