| Description | FPP29 is a novel, efficient, and safe peptide based FOXM1 PROTAC degrader. FPP29 significantly inhibits cell scratch healing, induces apoptosis, and suppresses clone formation. FPP29 has cytotoxicity (IC50 = 3.65 µM). FPP29 can be used for research on cancers such as liver cancer. (CPP: HY-FPP29 is a novel, efficient, and safe peptide based FOXM1 PROTAC degrader. FPP29 significantly inhibits cell scratch healing, induces apoptosis, and suppresses clone formation. FPP29 has cytotoxicity (IC50 = 3.65 µM). FPP29 can be used for research on cancers such as liver cancer. (CPP: HY-P0133, VHL Ligand: HY-P11493, Linker: HY-W013664, FOXM1 Ligand: HY-P11494)[1]... Read More | Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression[1]... Read More | Leucine dehydrogenase, Microorganism (EC 1.4.1.9) can be purified from Bacillus spheroides. Leucine dehydrogenase catalyzed the oxidative deamination of L-leucine, L-valine, L-isoleucine, L-norvaline, L-alpha-aminobutyrate, and L-norleucine, and the reductive amination of their keto analogues[1] | Pyruvate decarboxylase (Kp-IpdC) is a biochemical reagent that can be used as a biological material or organic compound for life science related research | Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake[1]... Read More |