Quadrupole Mass Spectrometer (MS) / Quadrupole Mass Analyzer

Quadrupole mass spectrometers are perhaps the simplest of mass spec instruments. Functioning effectively like a radio, the quadrupole MS – so-named because of its four charged rods, which run parallel to the flight paths of the ions it measures – filter ions by mass-to-charge ratio (m/z) by altering the voltages in the rods. Quadrupole mass spectrometers are available in a variety of formats, including a single quadrupole mass spectrometer, a triple quadrupole MS (three quadrupoles arranged in tandem), and a Q-TOF (a triple quad variant in which the third quadrupole is replaced with a time-of-flight mass analyzer).

Quadrupole mass analyzers are often used for targeted, quantitative applications and can be used either to measure one or a few given ions in a mixture, or to scan across a range of m/z values. Depending on the configuration, they can facilitate both MS and MS/MS applications. For instance, in a triple-quadrupole mass spectrometer, you can select ions for analysis in the first quadrupole, fragment them by collision with a gas in the second quadrupole, and analyze the resulting fragmentation ions in the third quadrupole.

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CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemLCMS-8050 Triple Quadrupole LC/MS/MS Mass SpectrometerGCMS-QP2020 NX Gas Chromatograph Mass Spectrometer (GC/MS)LCMS-2050 Mass SpectrometerLCMS-8060 Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-9030 Q-TOF Mass Spectrometer
Citations
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Catalog NumberLCMS-8050GCMS-QP2020 NXLCMS-2050LCMS-8060LCMS-9030
Price
Ionization Method(s)ESI, APCI, Dual IonizationEI, CI, NCIESI, APCI, Dual IonizationESI, APCI, Dual IonizationESI, APCI, DUIS, Micro
Mass AnalyzerQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsMetal quadrupole with pre-rodSingle QuadrupoleQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQuadrupole Time-of-Flight (Q-TOF)
Scanning Speed30,000 u/sec20,000 u/sec15,000 u/sec30,000 u/secUp to 100 Hz
Mass Range2 to 2000 m/z1.5 to 1090 m/zInquire2 to 2000 m/zm/z 10 to 40,000
DescriptionIncorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050 offers outstanding measurement speeds and quantitative performance. Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated ... Read MoreAdopting a proprietary multi-function ion source and a new large-capacity turbomolecular pump with heightened exhaust efficiency for all carrier gases including nitrogen, the rugged, high-sensitivity GCMS-QP2020 NX elevates GCMS performance to a new level. New Quick-CI and Smart SIM functionality ... Read MoreThe LCMS-2050 single quadrupole mass spectrometer combines the user-friendliness of an LC detector with the excellent performance of MS to provide a complete package of easy-to-use high-level performance and compactness. To make it accessible to all users, the system is enhanced with technology and ... Read MoreWith improved ion focusing technology, and incorporating Shimadzu’s proprietary ultrafast technologies, the LCMS-8060 creates a meaningful impact on trace quantitative detection. Combined with a robust design and easy maintenance, the LCMS-8060 is an ideal solution for better data quality and higher... Read MoreThe LCMS-9030 quadrupole time-of-fight (Q-TOF) mass spectrometer integrates the world’s fastest and most sensitive quadrupole technology with TOF architecture. A product of Shimadzu's engineering DNA, speed and effortless performance enable the LCMS-9030 to address qualitative and quantitative ... Read More
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