Quadrupole mass spectrometers are perhaps the simplest of mass spec instruments. Functioning effectively like a radio, the quadrupole MS – so-named because of its four charged rods, which run parallel to the flight paths of the ions it measures – filter ions by mass-to-charge ratio (m/z) by altering the voltages in the rods. Quadrupole mass spectrometers are available in a variety of formats, including a single quadrupole mass spectrometer, a triple quadrupole MS (three quadrupoles arranged in tandem), and a Q-TOF (a triple quad variant in which the third quadrupole is replaced with a time-of-flight mass analyzer).
Quadrupole mass analyzers are often used for targeted, quantitative applications and can be used either to measure one or a few given ions in a mixture, or to scan across a range of m/z values. Depending on the configuration, they can facilitate both MS and MS/MS applications. For instance, in a triple-quadrupole mass spectrometer, you can select ions for analysis in the first quadrupole, fragment them by collision with a gas in the second quadrupole, and analyze the resulting fragmentation ions in the third quadrupole.
Find, compare, and request a quote for quadrupole mass spectrometers across leading suppliers at Labcompare; including access to product citations, related published figures, and first-hand reviews from our scientific community.
| | | | | |
Company | Thermo Fisher Scientific | Thermo Fisher Scientific | Thermo Fisher Scientific | Thermo Fisher Scientific | Thermo Fisher Scientific |
Item | Thermo Scientific™Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ LC-MS/MS Mass Spectrometer | Thermo Scientific™ Exactive™ Plus EMR Orbitrap™ LC-MS System | Thermo Scientific™ Q Exactive™ Plus Hybrid Orbitrap™ Mass Spectrometer | Thermo Scientific™ TSQ™ 9610 Triple Quadrupole GC-MS/MS System | TSQ Quantis™ MD Mass Spectrometer |
Citations | | | | | |
Catalog Number | IQLAAEGAAPFALGMBDK | IQLAAEGAAPFALGMBDL | IQLAAEGAAPFALGMBDK | IQLAAAGABNFARPMBNB | IQLAAEGAAXFAQTMBLA |
Price | | | | | |
Ionization Method(s) | APCI, H-ESI | APCI, H-ESI | Inquire | Varies by model, AEI, EI, CI | Inquire |
Mass Analyzer | Hybrid Quadrupole / Orbitrap | Orbitrap | Hybrid Quadrupole-Orbitrap™ | Triple quadrupole | Triple quadrupole |
Scanning Speed | Up to 12 Hz | Up to 12 Hz | Up to 12 Hz | Inquire | Inquire |
Mass Range | 50 to 6,000 m/z | 350 to 20,000 m/z | 50 to 6,000 m/z | Inquire | 5 to 3000 m/z |
Description | Take Quanfirmation™ to the next level. The Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer introduced the revolutionary concept of Quanfirmation. The Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer takes Quanfirmation to the next level with increased Take Quanfirmation™ to the next level. The Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer introduced the revolutionary concept of Quanfirmation. The Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer takes Quanfirmation to the next level with increased performance and new options that enhance applications from confident DMPK qual/quan screening studies to characterization of intact monoclonal antibodies.
Features: - Advanced Quadrupole technology featuring Thermo Fisher segmented HyperQuad
- Resolving power up to 280,000
- Maximum scan speed 12 Hz
- Spectral multiplexing for enhanced duty cycle
- RF-Lens ion source for increased sensitivity
- Advanced Active Beam Guide intelligent ion beam management for high flux ion sources
- Intact Protein Mode option for characterizing intact proteins with ease
- Enhanced Resolution Option maximizing resolution at 280,000
... Read More | While analysis of denatured proteins may be the most common LC/MS protein analysis, many biopharmaceutical and biological research applications require analysis of proteins in their native (intact) state. The Thermo Scientific™ Exactive™ Plus EMR mass spectrometer combines unsurpassed high-While analysis of denatured proteins may be the most common LC/MS protein analysis, many biopharmaceutical and biological research applications require analysis of proteins in their native (intact) state. The Thermo Scientific™ Exactive™ Plus EMR mass spectrometer combines unsurpassed high-resolution accurate-mass Thermo Scientific™ Orbitrap™ analysis with an extended mass range (EMR) option to create an outstanding tool for investigating the structure, topology, and architecture of native-like tertiary and quaternary protein structures.... Read More | Take Quanfirmation™ to the next level. The Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer introduced the revolutionary concept of Quanfirmation. The Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer takes Quanfirmation to the next level with increased Take Quanfirmation™ to the next level. The Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer introduced the revolutionary concept of Quanfirmation. The Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer takes Quanfirmation to the next level with increased performance and new options that enhance applications from confident DMPK qual/quan screening studies to characterization of intact monoclonal antibodies.... Read More | The TSQ 9610 GC-MS/MS system is designed to revolutionize laboratory productivity by delivering unprecedented levels of performance and reduce cost per sample for the high-throughput environment. | Develop in vitro diagnostic tests for demanding quantitative analyses leveraging the enhanced sensitivity and remarkable speed and robustness of the Thermo Scientific™ TSQ Altis™ MD Series Mass Spectrometer. The TSQ Altis MD Series mass spectrometer, a Class I medical device, offers superb Develop in vitro diagnostic tests for demanding quantitative analyses leveraging the enhanced sensitivity and remarkable speed and robustness of the Thermo Scientific™ TSQ Altis™ MD Series Mass Spectrometer. The TSQ Altis MD Series mass spectrometer, a Class I medical device, offers superb analytical performance and features the maximum usability, sensitivity and robustness required for laboratory developed tests (LDTs) from clinical diagnostic laboratories. With superb analytical performance, this platform features maximum usability, sensitivity, and robustness.... Read More |
Get Quote | | | | | |