Description | The OmegaTOF system couples Shimadzu’s benchtop MALDI-TOF instrument platform (MALDI-8020) with established technology for high mass detection from CovalX Instruments Inc. The result is a user-friendly, compact platform that extends benchtop MALDI-TOF analysis to a mass range of 1.5 MegaDalton.
TheThe OmegaTOF system couples Shimadzu’s benchtop MALDI-TOF instrument platform (MALDI-8020) with established technology for high mass detection from CovalX Instruments Inc. The result is a user-friendly, compact platform that extends benchtop MALDI-TOF analysis to a mass range of 1.5 MegaDalton.
The high mass detection capabilities of the OmegaTOF allow the highest sensitivity for analyzing large biomolecules, protein interactions, peptides, oligonucleotides and polymers. This allows access to a full range of applications already developed and optimized by CovalX technologies, most notably characterizing monoclonal antibodies, such as IgG, IgA and IgM. Crosslinking chemistries developed by CovalX enable the OmegaTOF to measure intact protein interactions directly, providing insight into protein aggregation, mAb:antigen interactions, protein complex stoichiometry or ligand association/dissociation measurements.
The OmegaTOF offers:
- 200 Hz solid-state 355 nm laser featuring a class-leading two billion shots per lifetime
- Fast sample introduction using a load-lock chamber and quick sample stage movement
- Integrated barcode reader
- Patented TrueClean™ source cleaning
WideBore™ ion optics technologies that significantly reduce contamination from desorbed MALDI samples
- Ease-of-use
- Low maintenance
- Small footprint
- Quiet operation at <55 dB
OmegaTOF data can be directly imported into the latest versions of CovalX ComplexTracker software for protein interaction analysis. Tailored MALDI Solutions acquisition software features data security for regulatory compliance facilitated with password-controlled user login, encrypted data, and user traceability. ... Read More | Certain microorganisms can cause severe diseases and considerable damage, and need to be identified quickly and reliably. The easy-to-use AXIMA-iDPlus Microbial Identification System is the ideal tool to address these concerns. With AXIMA-iDPlus, cultured microorganisms can be directly applied to Certain microorganisms can cause severe diseases and considerable damage, and need to be identified quickly and reliably. The easy-to-use AXIMA-iDPlus Microbial Identification System is the ideal tool to address these concerns. With AXIMA-iDPlus, cultured microorganisms can be directly applied to the MALDI sample target and introduced to an AXIMA series MALDI-TOF mass spectrometer to revolutionize the daily routine in analytical and diagnostic laboratories.
Fast Response, Outstanding Recovery Rate
AXIMA-iDPlus can identify 380 clinical research samples within 5 hours in the high-throughput mode, less than one minute per sample. The results appear in a comprehensible spreadsheet format, exportable to common data processing software.
Gram-positive and gram-negative bacteria, yeast, fungi and spores are identified based on their characteristic MALDI-TOF MS fingerprints with up to 98% recovery rate down to sub-species level.
Substitutes Biochemical Standard Methods
No pre-selection of analytical methods is required; hands-on time is reduced and costs are cut dramatically.
Wide Range of Applications
AXIMA-iDPlus covers a wide range of applications in a number of industries, including diagnostics, pharmaceuticals, healthcare and food. Examples include:
- Diagnosis of human and veterinarian infectious pathogens
- Drug discovery process
- Culture collections
- Food and beverage manufacturing processes
Complementary Method
Designed for medium to high-throughput identification, AXIMA-iDPlus can be easily integrated into automated laboratory environments and any LIMS.... Read More | The MALDI-8030 is a dual-polarity, benchtop linear MALDI-TOF mass spectrometer that delivers outstanding performance in a compact footprint, making it an ideal choice for today’s increasingly demanding laboratories.
The dual-polarity ion source of the MALDI-8030 allows the flexibility to analyze a The MALDI-8030 is a dual-polarity, benchtop linear MALDI-TOF mass spectrometer that delivers outstanding performance in a compact footprint, making it an ideal choice for today’s increasingly demanding laboratories.
The dual-polarity ion source of the MALDI-8030 allows the flexibility to analyze a wide range of samples including proteins, peptides, oligonucleotides, lipids, glycans, polymers and small molecules. Its enhanced sample throughput, ease-of-use, low maintenance and small footprint make it ideal for all laboratories. Moreover, its quiet operation at <55 dB expands use beyond the conventional laboratory setting.
Key features include:
- Dual mode (positive/negative ion) MALDI-TOF
- 200 Hz solid-state laser, 355 nm, for class-leading two billion shots per lifetime
- Load-lock chamber for fast sample introduction
- UV laser-based source cleaning (patented) – enables seamless self-cleaning of the ion optics, without breaking vacuum and requiring the removal of the ion optics
- Patented WideBore™ ion optics technology – significantly reduces contamination from the desorbed MALDI sample
- Quiet operation (<55 dB)
In addition, the integrated barcode reader, when used with FlexiMass™-DS slides, is compatible with AuraSolution™ and SampleStation™ automated analysis software and can provide seamless tracking to reduce misidentification errors.
Tailored MALDI Solutions acquisition software features data security for regulatory compliance facilitated with password-controlled user login, encrypted data and user traceability.... Read More |