Maldi TOF Mass Spectrometer (MALDI TOF MS)

MALDI TOF mass spectrometers (matrix-assisted laser desorption/ionization/time-of-flight) are amongst the most popular mass spec instruments in biology. They combine two technologies, the “soft” MALDI ionization source and the TOF mass analyzer. The latter measures an ion’s mass-to-charge ratio (m/z) by measuring the time it takes to reach a detector. The former volatilizes and ionizes those molecules using a laser, a target, and an organic compound called a matrix. In MALDI, a sample (for instance, a collection of tryptic peptides) is mixed with matrix, spotted and dried (crystallized) on the surface of a metal target plate. Upon irradiation with laser light, the matrix absorbs the energy and converts it to heat, which then causes the sample to ionize and explode off the plate into the mass analyzer. MALDI TOF mass spectrometers come in two basic flavors, MALDI TOF MS and MALDI TOF/TOF MS; the latter enables tandem MS (MS/MS) studies.
CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemAxima Assurance MALDI Time of Flight Mass SpectrometerAXIMA-iD Plus Microorganism AnalysisMALDI-8020 EasyCare Benchtop Linear MALDI-TOF Mass SpectrometerMALDImini-1 Compact MALDI Digital Ion Trap Mass SpectrometerOmegaTOF Benchtop High Mass MALDI-TOF Mass Spectrometer
Citations
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Catalog NumberAXIMA AssuranceAXIMA-iD PlusMALDI-8020MALDImini-1OmegaTOF
Price
Ionization Method(s)MALDIMALDIMALDIMALDI ion sourceMALDI
Mass AnalyzerTOFMALDI-TOF MSTOFDigital Ion Trap (DIT)Time-of-Flight
Resolution>5000 FWHMInquire> 5000 FWHM – ACTH 18-39 (m/z 2465)Inquire>5000 FWHM – ACTH 18-39 (m/z 2465)
Scanning SpeedInquireInquireInquireInquireInquire
Mass Range1 kDa to 500 kDaVaries based on MALDI-TOF system usedm/z 1 - 500,000Inquirem/z 1,000–1,500,000Da
Description

An affordable, robust option for laboratories requiring routine manual or automated analysis of a wide variety of sample classes, the AXIMA Assurance provides high-quality, rapid MALDI mass spectra and an array of software tools for data processing and reporting. Incorporating a variable repetition

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Certain microorganisms can cause severe diseases and considerable damage, and need to be identified quickly and reliably. The easy-to-use AXIMA-iDPlus Microbial Identification System is the ideal tool to address these concerns. With AXIMA-iDPlus, cultured microorganisms can be directly applied to ... Read MoreThrough innovative instrument design, the space-saving linear MALDI-8020 achieves performance specifications similar to those of larger, more expensive MALDI-TOF models but in a significantly smaller footprint. The MALDI-8020 improves laboratory efficiency and accelerates analysis through a newly ... Read MoreInquireThe OmegaTOF system couples Shimadzu’s benchtop MALDI-TOF instrument platform (MALDI-8020) with established technology for high mass detection from CovalX Instruments Inc. The result is a user-friendly, compact platform that extends benchtop MALDI-TOF analysis to a mass range of 1.5 MegaDalton.

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