Maldi TOF Mass Spectrometer (MALDI TOF MS)

MALDI TOF mass spectrometers (matrix-assisted laser desorption/ionization/time-of-flight) are amongst the most popular mass spec instruments in biology. They combine two technologies, the “soft” MALDI ionization source and the TOF mass analyzer. The latter measures an ion’s mass-to-charge ratio (m/z) by measuring the time it takes to reach a detector. The former volatilizes and ionizes those molecules using a laser, a target, and an organic compound called a matrix. In MALDI, a sample (for instance, a collection of tryptic peptides) is mixed with matrix, spotted and dried (crystallized) on the surface of a metal target plate. Upon irradiation with laser light, the matrix absorbs the energy and converts it to heat, which then causes the sample to ionize and explode off the plate into the mass analyzer. MALDI TOF mass spectrometers come in two basic flavors, MALDI TOF MS and MALDI TOF/TOF MS; the latter enables tandem MS (MS/MS) studies.
CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemAxima Confidence MALDI TOF Mass SpectrometerAXIMA-iD Plus Microorganism AnalysisMALDI-8020 EasyCare Benchtop Linear MALDI-TOF Mass SpectrometerMALDImini-1 Compact MALDI Digital Ion Trap Mass SpectrometerMegaTOF Megadalton MALDI Mass Spectrometer
Citations
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Figures
Catalog NumberAxima ConfidenceAXIMA-iD PlusMALDI-8020MALDImini-1MegaTOF
Price
Ionization Method(s)MALDIMALDIMALDIMALDI ion sourceMALDI
Mass AnalyzerTOFMALDI-TOF MSTOFDigital Ion Trap (DIT)TOF
Resolution5000 FWHM in linear mode; 15000 FWHM in reflectron modeInquire> 5000 FWHM – ACTH 18-39 (m/z 2465)Inquire180 to 200 kDa
Scanning SpeedInquireInquireInquireInquire15 sec/position
Mass Range1 kDa to 500 kDaVaries based on MALDI-TOF system usedm/z 1 - 500,000Inquire0.01 to 1.5 Mda
Description

An affordable, robust option for routine sample analysis performed manually or automatically, the AXIMA Confidence offers reliable mass information and MS/MS-derived structural detail. A linear mode enables outstanding levels of analysis of high-molecular weight samples while the reflectron mode,

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Certain microorganisms can cause severe diseases and considerable damage, and need to be identified quickly and reliably. The easy-to-use AXIMA-iDPlus Microbial Identification System is the ideal tool to address these concerns. With AXIMA-iDPlus, cultured microorganisms can be directly applied to ... Read MoreThrough innovative instrument design, the space-saving linear MALDI-8020 achieves performance specifications similar to those of larger, more expensive MALDI-TOF models but in a significantly smaller footprint. The MALDI-8020 improves laboratory efficiency and accelerates analysis through a newly ... Read MoreInquireThe MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.

Features
  • Ultrahigh sensitivity
  • Detects macromolecules up to 1,500,000 Da
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