| Description | The AXIMA Performance is one of the most powerful tools in mass spectrometry, delivering information-rich spectra with greater sensitivity and higher confidence in identification. Extremely versatile, this MALDI TOF-TOF mass spectrometer utilizes state-of-the-art high energy MS/MS, delivers The AXIMA Performance is one of the most powerful tools in mass spectrometry, delivering information-rich spectra with greater sensitivity and higher confidence in identification. Extremely versatile, this MALDI TOF-TOF mass spectrometer utilizes state-of-the-art high energy MS/MS, delivers unparalleled flexibility in an ergonomic, robust and reliable research-grade system, and provides the pinnacle of performance for high-energy MS/MS interrogation of proteomics, biological and organic samples. Features: Highest Energy Collisions
A CID with a laboratory frame collisional energy of 20keV delivers true high-energy MS/MS and, together with the newly redesigned curved field reflectron, produces well-balanced, information-rich MS/MS data. The novel additional LMZ scan allows focus of the analysis to be directed around the low mass region of the MS/MS spectrum. Revolutionary Gating Technology
Allows optimal isolation of precursor ions with market-leading optimal precursor ion selection (>400 resolution FWHM), preventing the complication of overlapping fragmentation spectra from analytes with similar nominal masses. The resulting MS/MS spectra are easier to interpret and significant database search hits are more readily achieved. High Sensitivity/Resolution
Near axis laser irradiation provides enhanced ion transmission and sensitivity in all modes of operation. The unique reflectron design improves resolution, and enhanced calibration algorithms with easy-to-use software provide more accurate data. Outstanding Sensitivity with an uncompromised gridless design that ensures no MS/MS signal is lost. High-resolution MS Data in Reflectron Mode
At >20,000 FWHM, the AXIMA Performance enables more accurate and confident peptide mass fingerprinting. Uncompromised Linear Mass Range and Sensitivity
A highly optimized linear mode generates reproducible and sensitive results for very high mass compounds and complexes, extending the array of sample classes that may be analyzed. Low Sample Consumption allows many more MS/MS experiments to be performed on the same sample spot. Unparalleled Flexibility
Not just another proteomics workhorse, polymers, oligonucleotides, SNPs, metabolites, carbohydrates and small molecules, among others, may all be analyzed and processed. A variety of sample target formats, including standard microtiter plate format 96 or 384 well targets, can be used.
Like all AXIMA MALDI-TOF systems, the AXIMA Performance can be fully integrated with robotic sample preparation devices, including the AccuSpot MALDI plate spotter and CHIP chemical printer, to create application-specific platforms. Integration with the CHIP creates a powerful platform for tissue imaging, while using an AXIMA instrument with a Prominence GPC system and AccuSpot results in a fully automated platform for polymer analysis that delivers quick, detailed analysis of ultra-trace substances. ... Read More | An affordable, robust option for laboratories requiring routine manual or automated analysis of a wide variety of sample classes, the AXIMA Assurance provides high-quality, rapid MALDI mass spectra and an array of software tools for data processing and reporting. Incorporating a variable repetition An affordable, robust option for laboratories requiring routine manual or automated analysis of a wide variety of sample classes, the AXIMA Assurance provides high-quality, rapid MALDI mass spectra and an array of software tools for data processing and reporting. Incorporating a variable repetition rate 50Hz N2 laser, it is ideally suited for high-throughput QA/QC analysis of oligonucleotide/primers, synthetic peptides/proteins, polymers, and other small molecules. Features: High Sensitivity/Resolution:
A variable repetition rate 50 Hz N2 laser and advanced ion optics for enhanced ion transmission enable users to meet all sample throughput requirements. Pulsed extraction of ions from the MALDI source improves resolution, and enhanced calibration algorithms with easy-to-use software provide more accurate data. Positive and Negative Ion Modes Included as Standard:
Allows greater flexibility and extends the compound categories that may be analyzed. Patented Beam Blanker:
Removes unwanted low mass ions and prevents detector saturation. Unparalleled Flexibility:
A variety of sample target formats, including standard microtiter plate format 96 or 384 well targets, can be used. In addition, Fleximass™ microscope slides (plain or 48 well targets) and a wide variety of adaptors for unconventional sample layouts are available.
Like all AXIMA MALDI-TOF systems, the AXIMA Assurance can be fully integrated with robotic sample preparation devices, including the AccuSpot MALDI plate spotter and CHIP chemical printer, to create application-specific platforms. Integration with the CHIP creates a powerful platform for tissue imaging, while using an AXIMA instrument with a Prominence GPC system and AccuSpot results in a fully automated platform for polymer analysis that delivers quick, detailed analysis of ultra-trace substances. ... Read More | Certain microorganisms can cause severe diseases and considerable damage, and need to be identified quickly and reliably. The easy-to-use AXIMA-iDPlus Microbial Identification System is the ideal tool to address these concerns. With AXIMA-iDPlus, cultured microorganisms can be directly applied to Certain microorganisms can cause severe diseases and considerable damage, and need to be identified quickly and reliably. The easy-to-use AXIMA-iDPlus Microbial Identification System is the ideal tool to address these concerns. With AXIMA-iDPlus, cultured microorganisms can be directly applied to the MALDI sample target and introduced to an AXIMA series MALDI-TOF mass spectrometer to revolutionize the daily routine in analytical and diagnostic laboratories.
Fast Response, Outstanding Recovery Rate
AXIMA-iDPlus can identify 380 clinical research samples within 5 hours in the high-throughput mode, less than one minute per sample. The results appear in a comprehensible spreadsheet format, exportable to common data processing software.
Gram-positive and gram-negative bacteria, yeast, fungi and spores are identified based on their characteristic MALDI-TOF MS fingerprints with up to 98% recovery rate down to sub-species level.
Substitutes Biochemical Standard Methods
No pre-selection of analytical methods is required; hands-on time is reduced and costs are cut dramatically.
Wide Range of Applications
AXIMA-iDPlus covers a wide range of applications in a number of industries, including diagnostics, pharmaceuticals, healthcare and food. Examples include:
- Diagnosis of human and veterinarian infectious pathogens
- Drug discovery process
- Culture collections
- Food and beverage manufacturing processes
Complementary Method
Designed for medium to high-throughput identification, AXIMA-iDPlus can be easily integrated into automated laboratory environments and any LIMS.... Read More | The Benchtop MALDI-TOF Imaging Kit is ideal for users starting out in the world of biomolecular imaging. Used in conjunction with the compact benchtop MALDI-TOF 8020/8030 systems, it provides a welcoming platform by combining the ease of MALDI analysis with extremely intuitive software in an all-The Benchtop MALDI-TOF Imaging Kit is ideal for users starting out in the world of biomolecular imaging. Used in conjunction with the compact benchtop MALDI-TOF 8020/8030 systems, it provides a welcoming platform by combining the ease of MALDI analysis with extremely intuitive software in an all-inclusive imaging kit. The system can serve as an ideal teaching tool to introduce users to MALDI imaging. In addition, it offers a low-cost entry point to users who would like to see what MALDI imaging can offer for their workflow.
The benchtop systems are equipped with a fast sample stage and quick-load technology, which enable a short time-to-analysis while delivering low associated overhead costs with a long-life fast laser (200 Hz), the longer-life AeonDetectorTM and self-cleaning ion optics based on the Shimadzu TrueCleanTM technology.
The Benchtop MALDI-TOF Imaging Kit is a value-added package to complement existing and new users of the MALDI-8020 or MALDI-8030, expanding the already versatile capabilities of these systems. The kit includes everything users need to begin imaging experiments on their MALDI-8020 or MALDI-8030 system, including:
- Custom ITO-coated glass slides
- New custom glass slide holder
- Metal slides for those who prefer a reusable slide option
- Mask to facilitate sample mounting and to shield regions of the glass slide during matrix deposition
- Carrier to aid optical scanning
The MALDI Solutions IonView software (included in the kit) provides an easy workflow for the routine processing of MALDI images such as snapshots, overlays, and displays of regions of interest and pixel spectra.... Read More | The MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.
Features - Ultrahigh sensitivity
- Detects macromolecules up to 1,500,000 Da
The MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.
Features - Ultrahigh sensitivity
- Detects macromolecules up to 1,500,000 Da
- Stabilization of molecule using crosslinking reagent kits
- Fast, specific stabilization of protein interactions
- Also applicable for low mass applications
- Apple iPod Touch control
Applications - Antibody characterization
- Protein complexes characterization
- Therapeutic protein aggregates
- High mass MALDI imaging
- Inhibitors of protein-protein interactions
This product is only available in the United States.... Read More |