| Description | The Benchtop MALDI-TOF Imaging Kit is ideal for users starting out in the world of biomolecular imaging. Used in conjunction with the compact benchtop MALDI-TOF 8020/8030 systems, it provides a welcoming platform by combining the ease of MALDI analysis with extremely intuitive software in an all-The Benchtop MALDI-TOF Imaging Kit is ideal for users starting out in the world of biomolecular imaging. Used in conjunction with the compact benchtop MALDI-TOF 8020/8030 systems, it provides a welcoming platform by combining the ease of MALDI analysis with extremely intuitive software in an all-inclusive imaging kit. The system can serve as an ideal teaching tool to introduce users to MALDI imaging. In addition, it offers a low-cost entry point to users who would like to see what MALDI imaging can offer for their workflow.
The benchtop systems are equipped with a fast sample stage and quick-load technology, which enable a short time-to-analysis while delivering low associated overhead costs with a long-life fast laser (200 Hz), the longer-life AeonDetectorTM and self-cleaning ion optics based on the Shimadzu TrueCleanTM technology.
The Benchtop MALDI-TOF Imaging Kit is a value-added package to complement existing and new users of the MALDI-8020 or MALDI-8030, expanding the already versatile capabilities of these systems. The kit includes everything users need to begin imaging experiments on their MALDI-8020 or MALDI-8030 system, including:
- Custom ITO-coated glass slides
- New custom glass slide holder
- Metal slides for those who prefer a reusable slide option
- Mask to facilitate sample mounting and to shield regions of the glass slide during matrix deposition
- Carrier to aid optical scanning
The MALDI Solutions IonView software (included in the kit) provides an easy workflow for the routine processing of MALDI images such as snapshots, overlays, and displays of regions of interest and pixel spectra.... Read More | An affordable, robust option for routine sample analysis performed manually or automatically, the AXIMA Confidence offers reliable mass information and MS/MS-derived structural detail. A linear mode enables outstanding levels of analysis of high-molecular weight samples while the reflectron mode, An affordable, robust option for routine sample analysis performed manually or automatically, the AXIMA Confidence offers reliable mass information and MS/MS-derived structural detail. A linear mode enables outstanding levels of analysis of high-molecular weight samples while the reflectron mode, incorporating the patented, newly improved curved-field reflectron, provides high resolution and mass accuracy. Features: High Sensitivity/Resolution
A variable repetition rate 50 Hz N2 laser and advanced ion optics for enhanced ion transmission enable users to meet all sample throughput requirements. Pulsed extraction of ions from the MALDI source, in combination with the unique reflectron design, improves resolution, and enhanced calibration algorithms with easy-to-use software provide more accurate data. Easily Perform MS/MS
A seamless approach isolates ions of interest, and data-rich fragment ion spectra are quickly and simply acquired. The curved field reflectron design augments the low mass fragment region to provide additional information. Positive and Negative Ion Modes Included as Standard
Allows greater flexibility and extends the compound categories that may be analyzed. Patented Beam Blanker
Removes unwanted low mass ions and prevents detector saturation. Unparalleled Flexibility
A variety of sample target formats, including standard microtiter plate format 96 or 384 well targets, can be used. In addition, Fleximass™ microscope slides (plain or 48 well targets) and a wide variety of adaptors for unconventional sample layouts are available.
Like all AXIMA MALDI-TOF systems, the AXIMA Confidence can be fully integrated with robotic sample preparation devices, including the AccuSpot MALDI plate spotter and CHIP chemical printer, to create application-specific platforms. Integration with the CHIP creates a powerful platform for tissue imaging, while using an AXIMA instrument with a Prominence GPC system and AccuSpot results in a fully automated platform for polymer analysis that delivers quick, detailed analysis of ultra-trace substances. ... Read More | Through innovative instrument design, the space-saving linear MALDI-8020 achieves performance specifications similar to those of larger, more expensive MALDI-TOF models but in a significantly smaller footprint. The MALDI-8020 improves laboratory efficiency and accelerates analysis through a newly Through innovative instrument design, the space-saving linear MALDI-8020 achieves performance specifications similar to those of larger, more expensive MALDI-TOF models but in a significantly smaller footprint. The MALDI-8020 improves laboratory efficiency and accelerates analysis through a newly designed load-lock system for rapid sample target introduction and a solid-state laser for fast data acquisition speeds. Using linear time of flight, this compact MALDI-TOF system enables low-level detection of proteins, peptides and polymers, among other analytes. In addition, it easily accommodates standard laboratory workflows such as peptide mass finger printing for simple protein ID confirmation, in-source decay (ISD) and polymer distribution analysis.
Features: - Compact benchtop design
- Rapid loading and acquisition
- Automated source cleaning
- Integrated barcode scanner
The MALDI-8020, operated by MALDI Solutions software, is ideally suited for pharmaceutical QC labs as well as academic and industrial labs with limited laboratory space. With the addition of the MALDI-TOF Imaging Starter Kit, MS imaging on a benchtop system is now possible. MALDI Solutions offers intuitive, yet secure, operation, including security, audit trails and user management, to help meet 21 CFR Part 11 compliance. Additionally, the simple and intuitive user interface makes this an ideal teaching tool.... Read More | The MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.
Features - Ultrahigh sensitivity
- Detects macromolecules up to 1,500,000 Da
The MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.
Features - Ultrahigh sensitivity
- Detects macromolecules up to 1,500,000 Da
- Stabilization of molecule using crosslinking reagent kits
- Fast, specific stabilization of protein interactions
- Also applicable for low mass applications
- Apple iPod Touch control
Applications - Antibody characterization
- Protein complexes characterization
- Therapeutic protein aggregates
- High mass MALDI imaging
- Inhibitors of protein-protein interactions
This product is only available in the United States.... Read More | The OmegaTOF system couples Shimadzu’s benchtop MALDI-TOF instrument platform (MALDI-8020) with established technology for high mass detection from CovalX Instruments Inc. The result is a user-friendly, compact platform that extends benchtop MALDI-TOF analysis to a mass range of 1.5 MegaDalton.
TheThe OmegaTOF system couples Shimadzu’s benchtop MALDI-TOF instrument platform (MALDI-8020) with established technology for high mass detection from CovalX Instruments Inc. The result is a user-friendly, compact platform that extends benchtop MALDI-TOF analysis to a mass range of 1.5 MegaDalton.
The high mass detection capabilities of the OmegaTOF allow the highest sensitivity for analyzing large biomolecules, protein interactions, peptides, oligonucleotides and polymers. This allows access to a full range of applications already developed and optimized by CovalX technologies, most notably characterizing monoclonal antibodies, such as IgG, IgA and IgM. Crosslinking chemistries developed by CovalX enable the OmegaTOF to measure intact protein interactions directly, providing insight into protein aggregation, mAb:antigen interactions, protein complex stoichiometry or ligand association/dissociation measurements.
The OmegaTOF offers: - 200 Hz solid-state 355 nm laser featuring a class-leading two billion shots per lifetime
- Fast sample introduction using a load-lock chamber and quick sample stage movement
- Integrated barcode reader
- Patented TrueClean™ source cleaning
WideBore™ ion optics technologies that significantly reduce contamination from desorbed MALDI samples - Ease-of-use
- Low maintenance
- Small footprint
- Quiet operation at <55 dB
OmegaTOF data can be directly imported into the latest versions of CovalX ComplexTracker software for protein interaction analysis. Tailored MALDI Solutions acquisition software features data security for regulatory compliance facilitated with password-controlled user login, encrypted data, and user traceability. ... Read More |