Maldi TOF Mass Spectrometer (MALDI TOF MS)

MALDI TOF mass spectrometers (matrix-assisted laser desorption/ionization/time-of-flight) are amongst the most popular mass spec instruments in biology. They combine two technologies, the “soft” MALDI ionization source and the TOF mass analyzer. The latter measures an ion’s mass-to-charge ratio (m/z) by measuring the time it takes to reach a detector. The former volatilizes and ionizes those molecules using a laser, a target, and an organic compound called a matrix. In MALDI, a sample (for instance, a collection of tryptic peptides) is mixed with matrix, spotted and dried (crystallized) on the surface of a metal target plate. Upon irradiation with laser light, the matrix absorbs the energy and converts it to heat, which then causes the sample to ionize and explode off the plate into the mass analyzer. MALDI TOF mass spectrometers come in two basic flavors, MALDI TOF MS and MALDI TOF/TOF MS; the latter enables tandem MS (MS/MS) studies.
CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemiMScope QT Imaging Mass MicroscopeAxima Assurance MALDI Time of Flight Mass SpectrometerAxima Confidence MALDI TOF Mass SpectrometerMALDI-8020 EasyCare Benchtop Linear MALDI-TOF Mass SpectrometerMALDImini-1 Compact MALDI Digital Ion Trap Mass Spectrometer
Citations
Figures
Catalog NumberiMScope QTAXIMA AssuranceAxima ConfidenceMALDI-8020MALDImini-1
Price
Ionization Method(s)Atmospheric Pressure MALDI (AP-MALDI)MALDIMALDIMALDIMALDI ion source
Mass AnalyzerQ-TOFTOFTOFTOFDigital Ion Trap (DIT)
ResolutionInquire>5000 FWHM5000 FWHM in linear mode; 15000 FWHM in reflectron mode> 5000 FWHM – ACTH 18-39 (m/z 2465)Inquire
Scanning SpeedInquireInquireInquireInquireInquire
Mass RangeInquire1 kDa to 500 kDa1 kDa to 500 kDam/z 1 - 500,000Inquire
DescriptionInquire

An affordable, robust option for laboratories requiring routine manual or automated analysis of a wide variety of sample classes, the AXIMA Assurance provides high-quality, rapid MALDI mass spectra and an array of software tools for data processing and reporting. Incorporating a variable repetition

... Read More

An affordable, robust option for routine sample analysis performed manually or automatically, the AXIMA Confidence offers reliable mass information and MS/MS-derived structural detail. A linear mode enables outstanding levels of analysis of high-molecular weight samples while the reflectron mode,

... Read More
Through innovative instrument design, the space-saving linear MALDI-8020 achieves performance specifications similar to those of larger, more expensive MALDI-TOF models but in a significantly smaller footprint. The MALDI-8020 improves laboratory efficiency and accelerates analysis through a newly ... Read MoreInquire
Get Quote