Maldi TOF Mass Spectrometer (MALDI TOF MS)

MALDI TOF mass spectrometers (matrix-assisted laser desorption/ionization/time-of-flight) are amongst the most popular mass spec instruments in biology. They combine two technologies, the “soft” MALDI ionization source and the TOF mass analyzer. The latter measures an ion’s mass-to-charge ratio (m/z) by measuring the time it takes to reach a detector. The former volatilizes and ionizes those molecules using a laser, a target, and an organic compound called a matrix. In MALDI, a sample (for instance, a collection of tryptic peptides) is mixed with matrix, spotted and dried (crystallized) on the surface of a metal target plate. Upon irradiation with laser light, the matrix absorbs the energy and converts it to heat, which then causes the sample to ionize and explode off the plate into the mass analyzer. MALDI TOF mass spectrometers come in two basic flavors, MALDI TOF MS and MALDI TOF/TOF MS; the latter enables tandem MS (MS/MS) studies.
CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemMegaTOF Megadalton MALDI Mass SpectrometerAXIMA-iD Plus Microorganism AnalysisBenchtop MALDI Imaging KitiMScope QT Imaging Mass MicroscopeMALDI-8020 EasyCare Benchtop Linear MALDI-TOF Mass Spectrometer
Citations
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Catalog NumberMegaTOFAXIMA-iD PlusBenchtop MALDI ImagingiMScope QTMALDI-8020
Price
Ionization Method(s)MALDIMALDIInquireAtmospheric Pressure MALDI (AP-MALDI)MALDI
Mass AnalyzerTOFMALDI-TOF MSInquireQ-TOFTOF
Resolution180 to 200 kDaInquireInquireInquire> 5000 FWHM – ACTH 18-39 (m/z 2465)
Scanning Speed15 sec/positionInquireFastMS feature - with the 200 Hz laser, fast sample slide introduction ( <3 min), and quick sample stage – provides the speed to attain up to 15 pixels per second (lipid imaging acquisition (100 to 1200 m/z) at 50 µm spacing using an the accumulation rate of 10 shots/profile).InquireInquire
Mass Range0.01 to 1.5 MdaVaries based on MALDI-TOF system usedInquireInquirem/z 1 - 500,000
DescriptionThe MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.

Features
  • Ultrahigh sensitivity
  • Detects macromolecules up to 1,500,000 Da
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Certain microorganisms can cause severe diseases and considerable damage, and need to be identified quickly and reliably. The easy-to-use AXIMA-iDPlus Microbial Identification System is the ideal tool to address these concerns. With AXIMA-iDPlus, cultured microorganisms can be directly applied to ... Read MoreThe Benchtop MALDI-TOF Imaging Kit is ideal for users starting out in the world of biomolecular imaging. Used in conjunction with the compact benchtop MALDI-TOF 8020/8030 systems, it provides a welcoming platform by combining the ease of MALDI analysis with extremely intuitive software in an all-... Read MoreInquireThrough innovative instrument design, the space-saving linear MALDI-8020 achieves performance specifications similar to those of larger, more expensive MALDI-TOF models but in a significantly smaller footprint. The MALDI-8020 improves laboratory efficiency and accelerates analysis through a newly ... Read More
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