Description | Covering the complete range from micro (0.1 µL/min) to semi-micro (500 µL/min), Nexera Mikros allows operators to realize high sensitivity with the reliability and ruggedness of HPLC. A newly designed micro ESI source provides greater than ten times the sensitivity of standard UHPLC-MS Covering the complete range from micro (0.1 µL/min) to semi-micro (500 µL/min), Nexera Mikros allows operators to realize high sensitivity with the reliability and ruggedness of HPLC. A newly designed micro ESI source provides greater than ten times the sensitivity of standard UHPLC-MS systems, while the system’s UF-Link allows operators to correctly and easily connect any microflow column to ensure a zero-dead volume connection every time.
- Sensitivity gains of greater than 10X can be seen over conventional LCMS for assays of small molecules, peptides and proteins.
- Micro-ESI LCMS source designed for optimal sensitivity and ease of use. An X–Y adjustable stage and viewing camera allow for easy ESI spray needle adjustment
- Column oven mounted on the LCMS to minimize the volume between the exit of the column and the ESI needle.
- Proprietary UF-Link technology makes robust and correct connections of microflow columns a breeze
- Fast, accurate, reproducible autosampler with extremely low carry-over; injection volume ranges from 0.1 to 50 µL
- Consistent peak retention times and peak areas
... Read More | The LCMS-2050 single quadrupole mass spectrometer combines the user-friendliness of an LC detector with the excellent performance of MS to provide a complete package of easy-to-use high-level performance and compactness. To make it accessible to all users, the system is enhanced with technology and The LCMS-2050 single quadrupole mass spectrometer combines the user-friendliness of an LC detector with the excellent performance of MS to provide a complete package of easy-to-use high-level performance and compactness. To make it accessible to all users, the system is enhanced with technology and functions to ensure that even technicians unfamiliar with mass spectrometers can easily and efficiently perform analysis. While delivering operational convenience on par with an LC detector, the LCMS-2050 can rapidly analyze compounds over a wide mass range with high sensitivity.
Key features/benefits:
- Combined Dual Ion Source (heated electrospray and atmospheric pressure ionization) can analyze a wide range of compounds from multiple chemical classes
- Ultrafast technology, including a 15,000 u/sec scan speed and polarity switching time of 10 msec, maintains high data quality while improving overall throughout
- Can be incorporated as one component in an LC system
- Can be used like an LC that operators simply turn on and use, enabling everything from MS data acquisition to data analysis
- Vacuum system starts up in only six minutes for MS data acquisition
- System Check function – injects a standard sample automatically, checks the mass accuracy, resolution, and spectral intensity, as well as instrument status
- Easy system maintenance maximizes instrument uptime
The LabSolutions LCMS workstation for the LCMS-2050 can control the LC and MS instruments simultaneously. MS data and data obtained from other LC detectors can be analyzed on the same date review platform. It is also equipped with Analytical Intelligence functions for data analysis to make laboratory operations more efficient. The LC/MS chromatograms and UV/MS spectra can be displayed in a single window, which makes it easy to review data. Mass information can also be annotated on the UV chromatogram.... Read More | Incorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050 offers outstanding measurement speeds and quantitative performance. Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated Incorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050 offers outstanding measurement speeds and quantitative performance. Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated electrospray source and ultra-efficient collision cell.. Combine with Shimadzu’s world-leading UHPLC systems for an unmatched level of performance.
Features:- Ultrafast polarity switching (5 msec) – maintains constant quality and sensitivity with no loss of quantitative accuracy
- Ultra-high-speed scan rate of 30,000 u/sec – obtains high-quality mass spectra, even during high-speed analysis
- Ultrafast MRM transition speeds, up to 555 MRMs per second
- Newly developed heated ESI probe facilitates ionization – allows for high-sensitivity analysis of a wide range of compounds
- High-efficiency CID cell – maintains signal intensity and suppresses crosstalk, even for high-speed or simultaneous multicomponent analysis
Intuitive LabSolutions software allows for simplified instrument control, diverse data handling, and integration with regulatory compliance requirements. In addition, optional LabSolutions Insight data review software, supporting review-by-exception, dramatically improves the speed and efficiency of multi-analyte data analysis.... Read More | Shimadzu's most powerful tandem mass spectrometer, the triple quad LCMS-8060NX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity. Incorporation of a new IonFocus electrospray unit and newly designed ion guides deliver robust operation Shimadzu's most powerful tandem mass spectrometer, the triple quad LCMS-8060NX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity. Incorporation of a new IonFocus electrospray unit and newly designed ion guides deliver robust operation through reduced matrix effects and less contamination inside the instrument, resulting in maximized uptime, the utmost in data quality, and a more efficient analytical workflow.
Ion focus lenses in the state-of-the-art integrated electrospray probe propel ions into the LCMS-8060NX with the greatest of efficiency.
The heat assist design increases desolvation efficiency and promotes superior ionization of a wide range of compounds.
Unique UFsweeper technology effectively sweeps ions from the collision cell without deceleration, maintaining high-sensitivity analysis even at high acquisition speeds.
Ion guides increase robustness while maintaining high ion transmission efficiency.
Consumable parts like the ESI spray needle and the inlet desolvation line (DL) can be changed quickly and easily without breaking vacuum.
LabSolutions LCMS workstation software offers total operator support, from analysis to data processing. The LabSolutions Connect/LabSolutions Insight platform supports the entire analysis workflow, including project file management, optimization of MRM and interface parameters, efficient verification of quantitative results, simple method and batch creation and verification of quantitative results.... Read More | The Nexera QX Multiplex LC-MS/MS System uses multiple, alternating sample introduction streams for continuous operation of the mass spectrometer to significantly increase laboratory throughput and profitability.
- Multiple stream technology eliminates waiting for column equilibration and system
The Nexera QX Multiplex LC-MS/MS System uses multiple, alternating sample introduction streams for continuous operation of the mass spectrometer to significantly increase laboratory throughput and profitability.
- Multiple stream technology eliminates waiting for column equilibration and system flushing
- UHPLC autosamplers, stream-dedicated injection valves and washing pumps deliver ultra-fast performance with ultra-low carryover
- Automates flow line rinsing of each analytical stream to mitigate carryover from extreme samples
- Utilizes the LCMS-8060NX triple quadrupole mass spectrometer, which delivers industry-leading robustness, sensitivity and detection speeds.
Newly developed QX Solution software offers an intelligent, automated single point of control for multiple UHPLC streams and the mass spectrometer for a genuine, multiplexed workflow. Specifically designed for the high-throughput laboratory, the system features the easy import of spreadsheet sample batches.... Read More |