LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanySCIEXSCIEX
ItemSelexION Differential Mobility SpectrometryZenoTOF 7600 system
Citations
Catalog NumberSelexIONZenoTOF 7600
Price
Ionization Method(s)InquireAPCI and ESI modes
Mass AnalyzerInquireTOF
Scanning SpeedInquireup to 25 Hz (25 spectra per second)
ResolutionInquireEqual to or greater than 42,000 (FWHM) measured on the [M+6H]6+ charge isotope cluster for bovine insulin at m/z 956
DescriptionLC-MS/MS assay development can be challenging, particularly for analytes that coelute with contaminants or become buried within background noise. The SCIEX SelexION Differential Mobility Separation device (DMS) provides an extra level of selectivity so you can resolve difficult analytes and achieve ... Read MoreA powerful leap in proprietary innovation, this high-resolution accurate mass system combines the power of Zeno trap pulsing with EAD fragmentation technology (electron activated dissociation) to uncover structural information, previously inaccessible, and drive the limits of quantification ... Read More
QuantityInquireEA
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