| Ionization Method(s) | ESI, APCI, Dual Ionization | ESI, APCI, Dual Ionization, Micro-ESI | ESI, APCI, Dual Ionization, Micro-ESI | Micro-ESI |
| Description | The LCMS-2050 single quadrupole mass spectrometer combines the user-friendliness of an LC detector with the excellent performance of MS to provide a complete package of easy-to-use high-level performance and compactness. To make it accessible to all users, the system is enhanced with technology and The LCMS-2050 single quadrupole mass spectrometer combines the user-friendliness of an LC detector with the excellent performance of MS to provide a complete package of easy-to-use high-level performance and compactness. To make it accessible to all users, the system is enhanced with technology and functions to ensure that even technicians unfamiliar with mass spectrometers can easily and efficiently perform analysis. While delivering operational convenience on par with an LC detector, the LCMS-2050 can rapidly analyze compounds over a wide mass range with high sensitivity.
Key features/benefits: - Combined Dual Ion Source (heated electrospray and atmospheric pressure ionization) can analyze a wide range of compounds from multiple chemical classes
- Ultrafast technology, including a 15,000 u/sec scan speed and polarity switching time of 10 msec, maintains high data quality while improving overall throughout
- Can be incorporated as one component in an LC system
- Can be used like an LC that operators simply turn on and use, enabling everything from MS data acquisition to data analysis
- Vacuum system starts up in only six minutes for MS data acquisition
- System Check function – injects a standard sample automatically, checks the mass accuracy, resolution, and spectral intensity, as well as instrument status
- Easy system maintenance maximizes instrument uptime
The LabSolutions LCMS workstation for the LCMS-2050 can control the LC and MS instruments simultaneously. MS data and data obtained from other LC detectors can be analyzed on the same date review platform. It is also equipped with Analytical Intelligence functions for data analysis to make laboratory operations more efficient. The LC/MS chromatograms and UV/MS spectra can be displayed in a single window, which makes it easy to review data. Mass information can also be annotated on the UV chromatogram.... Read More | Incorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050RX offers outstanding measurement speeds and quantitative performance.
Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated Incorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050RX offers outstanding measurement speeds and quantitative performance.
Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated electrospray source and ultra-efficient collision cell.
Combine with Shimadzu’s world-leading UHPLC systems for an unmatched level of performance.
Features:
- Ultrafast polarity switching (5 msec) – maintains constant quality and sensitivity with no loss of quantitative accuracy
- Ultra-high-speed scan rate of 30,000 u/sec – obtains high-quality mass spectra, even during high-speed analysis
- Ultrafast MRM transition speeds, up to 555 MRMs per second
- Heated ESI probe – promotes the ionization of wide range of targeted compounds
- CoreSpray™ gas delivery system – enhances reliability by increasing gas flow and improving nebulizer coaxiality
- High-efficiency CID cell – maintains signal intensity and suppresses crosstalk, even for high-speed or simultaneous multicomponent analysis
- Performance Concierge – Automatically monitors system performance, provides proactive maintenance alerts, and reduces instrument downtime through predictive diagnostics
- Easy maintenance – Changing the ESI capillary and the desolvation line (DL) can be quickly replaced without breaking vacuum
Intuitive LabSolutions software allows for simplified instrument control, diverse data handling, and integration with regulatory compliance requirements.
Optional LabSolutions Insight data review software, supporting review-by-exception, dramatically improves the speed and efficiency of multi-analyte data analysis.
In addition, LabSolutions MRM Connect automates MRM optimization to create high sensitivity quantitative LC-MS/MS methods.
... Read More | Shimadzu’s LCMS RX series of triple quadrupole mass spectrometry instruments are supported by integrated hardware and software technologies to ensure ultrafast performance and reliable, robust results at lower operating costs, even under the most challenging and dynamic laboratory environments. The Shimadzu’s LCMS RX series of triple quadrupole mass spectrometry instruments are supported by integrated hardware and software technologies to ensure ultrafast performance and reliable, robust results at lower operating costs, even under the most challenging and dynamic laboratory environments. The RX Series incorporates patented Ultra Fast Mass Spectrometry (UFMS) technologies to deliver a polarity switching time of 5 msec, data acquisition scan speed of 30,000 u/sec, and ultra-fast MRM measurements up to 555 ch/sec, setting a new standard for dependable data acquisition and robust performance.
A suite of innovative technologies introduced with the RX series sets a new benchmark for reliability, resilience and responsibility:
- CoreSpray™ gas delivery system – enhances reliability by increasing gas flow and improving nebulizer coaxiality. This improves the heat distribution of the ionization source, ensuring unparalleled sample ionization, significantly enhancing the reliability of analytical data.
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IonFocus™ electrode – effectively removes matrix contaminants, resulting in lower noise levels, superior data quality and reduced maintenance needs.
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Heated ESI Probe – promotes the ionization of wide range of targeted compounds
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Performance Concierge – proactively evaluates system performance with a standard solution, troubleshoots problems, and notifies operators of maintenance needs, effectively minimizing instrument downtime.
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Enhanced software capabilities – autonomously monitor the system, reducing the need for manual intervention
The RX series consists of the following models:
- LCMS-8060RX: premier system offers world-class sensitivity, rapid analysis capabilities and remarkable robustness
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LCMS-8050RX: high-speed operation, excellent sensitivity, and trusted reliability in a robust, easy-to-use design
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LCMS-8045RX: ideal for routine analysis, delivering a balance of robustness, sensitivity and cost-effectiveness
The LCMS RX series enables responsible operation for lower laboratory costs and reduced environmental impact. These instruments provide an Ecology Mode function that automatically checks system status and shuts the instrument down after sample queues are completed. This reduction in power consumption minimizes the running cost of the laboratory and consumes less resources.... Read More | Covering the complete range from micro (0.1 µL/min) to semi-micro (500 µL/min), Nexera Mikros allows operators to realize high sensitivity with the reliability and ruggedness of HPLC. A newly designed micro ESI source provides greater than ten times the sensitivity of standard UHPLC-MS Covering the complete range from micro (0.1 µL/min) to semi-micro (500 µL/min), Nexera Mikros allows operators to realize high sensitivity with the reliability and ruggedness of HPLC. A newly designed micro ESI source provides greater than ten times the sensitivity of standard UHPLC-MS systems, while the system’s UF-Link allows operators to correctly and easily connect any microflow column to ensure a zero-dead volume connection every time.
- Sensitivity gains of greater than 10X can be seen over conventional LCMS for assays of small molecules, peptides and proteins.
- Micro-ESI LCMS source designed for optimal sensitivity and ease of use. An X–Y adjustable stage and viewing camera allow for easy ESI spray needle adjustment
- Column oven mounted on the LCMS to minimize the volume between the exit of the column and the ESI needle.
- Proprietary UF-Link technology makes robust and correct connections of microflow columns a breeze
- Fast, accurate, reproducible autosampler with extremely low carry-over; injection volume ranges from 0.1 to 50 µL
- Consistent peak retention times and peak areas
... Read More |