| Ionization Method(s) | ESI, APCI, Dual Ionization, Micro-ESI | ESI, APCI, Dual Ionization, Micro-ESI | Micro-ESI | ESI, APCI, Dual Ionization |
| Description | Shimadzu’s LCMS RX series of triple quadrupole mass spectrometry instruments are supported by integrated hardware and software technologies to ensure ultrafast performance and reliable, robust results at lower operating costs, even under the most challenging and dynamic laboratory environments. The Shimadzu’s LCMS RX series of triple quadrupole mass spectrometry instruments are supported by integrated hardware and software technologies to ensure ultrafast performance and reliable, robust results at lower operating costs, even under the most challenging and dynamic laboratory environments. The RX Series incorporates patented Ultra Fast Mass Spectrometry (UFMS) technologies to deliver a polarity switching time of 5 msec, data acquisition scan speed of 30,000 u/sec, and ultra-fast MRM measurements up to 555 ch/sec, setting a new standard for dependable data acquisition and robust performance.
A suite of innovative technologies introduced with the RX series sets a new benchmark for reliability, resilience and responsibility:
- CoreSpray™ gas delivery system – enhances reliability by increasing gas flow and improving nebulizer coaxiality. This improves the heat distribution of the ionization source, ensuring unparalleled sample ionization, significantly enhancing the reliability of analytical data.
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IonFocus™ electrode – effectively removes matrix contaminants, resulting in lower noise levels, superior data quality and reduced maintenance needs.
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Heated ESI Probe – promotes the ionization of wide range of targeted compounds
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Performance Concierge – proactively evaluates system performance with a standard solution, troubleshoots problems, and notifies operators of maintenance needs, effectively minimizing instrument downtime.
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Enhanced software capabilities – autonomously monitor the system, reducing the need for manual intervention
The RX series consists of the following models:
- LCMS-8060RX: premier system offers world-class sensitivity, rapid analysis capabilities and remarkable robustness
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LCMS-8050RX: high-speed operation, excellent sensitivity, and trusted reliability in a robust, easy-to-use design
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LCMS-8045RX: ideal for routine analysis, delivering a balance of robustness, sensitivity and cost-effectiveness
The LCMS RX series enables responsible operation for lower laboratory costs and reduced environmental impact. These instruments provide an Ecology Mode function that automatically checks system status and shuts the instrument down after sample queues are completed. This reduction in power consumption minimizes the running cost of the laboratory and consumes less resources.... Read More | The triple quad LCMS-8060RX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity.
A heat-assisted electrospray ionization probe delivers a highly efficient desolvation process that promotes the ionization of a wide range of target compounds The triple quad LCMS-8060RX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity.
A heat-assisted electrospray ionization probe delivers a highly efficient desolvation process that promotes the ionization of a wide range of target compounds while the systems unique IonFocus™ electrode efficiently delivers ions into the mass spectrometer, resulting in lower noise levels, superior data quality and reduced maintenance needs.
Additional features include:
- CoreSpray™ gas delivery system – enhances reliability by increasing gas flow and improving nebulizer coaxiality.
- Ultrafast high-voltage power supply – enables sensitive and stable signal detection
- UFsweeper Collision Cell – delivers fast and accurate MRM quantitation; high-speed and high-efficiency CID occurs as ions are accelerated through the cell, enabling multi-component analysis with little signal degradation or crosstalk
- Scan speed of 30,000 u/s
- 5 ms polarity switching time
- Ultra-fast MRM measurements up to 555 ch/sec
- IonFocus™ electrode – effectively removes matrix contaminants, resulting in lower noise levels, superior data quality and reduced maintenance needs
- Easy maintenance – Consumable parts like the ESI spray needle and the inlet desolvation line (DL) can be changed quickly and easily without breaking vacuum.
- Performance Concierge – Automatically monitors system performance, provides proactive maintenance alerts, and reduces instrument downtime through predictive diagnostics.
LabSolutions LCMS workstation software offers total operator support, from analysis to data processing.
The LabSolutions Connect/LabSolutions Insight platform supports the entire analysis workflow, including:
- Project file management
- Optimization of MRM and interface parameters
- Efficient verification of quantitative results
- Simple method and batch creation
- Verification of quantitative results
... Read More | Covering the complete range from micro (0.1 µL/min) to semi-micro (500 µL/min), Nexera Mikros allows operators to realize high sensitivity with the reliability and ruggedness of HPLC. A newly designed micro ESI source provides greater than ten times the sensitivity of standard UHPLC-MS Covering the complete range from micro (0.1 µL/min) to semi-micro (500 µL/min), Nexera Mikros allows operators to realize high sensitivity with the reliability and ruggedness of HPLC. A newly designed micro ESI source provides greater than ten times the sensitivity of standard UHPLC-MS systems, while the system’s UF-Link allows operators to correctly and easily connect any microflow column to ensure a zero-dead volume connection every time.
- Sensitivity gains of greater than 10X can be seen over conventional LCMS for assays of small molecules, peptides and proteins.
- Micro-ESI LCMS source designed for optimal sensitivity and ease of use. An X–Y adjustable stage and viewing camera allow for easy ESI spray needle adjustment
- Column oven mounted on the LCMS to minimize the volume between the exit of the column and the ESI needle.
- Proprietary UF-Link technology makes robust and correct connections of microflow columns a breeze
- Fast, accurate, reproducible autosampler with extremely low carry-over; injection volume ranges from 0.1 to 50 µL
- Consistent peak retention times and peak areas
... Read More | The Nexera QX Multiplex LC-MS/MS System uses multiple, alternating sample introduction streams for continuous operation of the mass spectrometer to significantly increase laboratory throughput and profitability.
- Multiple stream technology eliminates waiting for column equilibration and system
The Nexera QX Multiplex LC-MS/MS System uses multiple, alternating sample introduction streams for continuous operation of the mass spectrometer to significantly increase laboratory throughput and profitability.
- Multiple stream technology eliminates waiting for column equilibration and system flushing
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UHPLC autosamplers, stream-dedicated injection valves and washing pumps deliver ultra-fast performance with ultra-low carryover
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Automates flow line rinsing of each analytical stream to mitigate carryover from extreme samples
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Online sample cleanup – Automated online sample preparation avoids errors caused by manual handling and maximizes throughput.
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Multiple configurations available
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Utilizes the LCMS-8060NX triple quadrupole mass spectrometer, which delivers industry-leading robustness, sensitivity and detection speeds.
Dedicated QX Solution software offers a single point of control for multiple UHPLC streams and the mass spectrometer. By incorporating Analytical Intelligence, such as automatic carryover detection and evaluation, automatic rinsing, and high-concentration automatic detection, QX software ensures robust operation for prolonged unattended analysis.... Read More |