LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyShimadzuShimadzuShimadzuShimadzu
ItemLCMS-8050RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-8060RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-TQ RX Series Triple Quadrupole LC-MS/MSNexera QX Multiplex LC-MS
Citations
Figures
(2)
Catalog NumberLCMS-8050RXLCMS-8060RXLCMS RX SeriesNexera QX
Price
Ionization Method(s)ESI, APCI, Dual Ionization, Micro-ESIESI, APCI, Dual Ionization, Micro-ESIESI, APCI, Dual Ionization, Micro-ESIESI, APCI, Dual Ionization
Mass AnalyzerQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rods
Scanning Speed30,000 u/secMax. 30,000 u/sec (in all scan modes) (0.1 u step: 300,000 data points/sec)Max. 30,000 u/sec (in all scan modes) (0.1 u step: 300,000 data points/sec)Inquire
ResolutionR < 0.7 u FWHMR < 0.7 u FWHM and adjustable to 0.5 uR < 0.7 u FWHM and adjustable to 0.5 uInquire
DescriptionIncorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050RX offers outstanding measurement speeds and quantitative performance.
Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated
... Read More
The triple quad LCMS-8060RX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity.
A heat-assisted electrospray ionization probe delivers a highly efficient desolvation process that promotes the ionization of a wide range of target compounds
... Read More
Shimadzu’s LCMS RX series of triple quadrupole mass spectrometry instruments are supported by integrated hardware and software technologies to ensure ultrafast performance and reliable, robust results at lower operating costs, even under the most challenging and dynamic laboratory environments. The ... Read MoreThe Nexera QX Multiplex LC-MS/MS System uses multiple, alternating sample introduction streams for continuous operation of the mass spectrometer to significantly increase laboratory throughput and profitability.

  • Multiple stream technology eliminates waiting for column equilibration and system
... Read More
QuantityEAEAEAEA
TypeInquireTriple Quad LC-MS/MSTriple Quad LC-MS/MSInquire
Get Quote

Articles