LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ ISQ™ EC Single Quadrupole Mass SpectrometerQ Exactive™ UHMR Hybrid Quadrupole-Orbitrap™ Mass SpectrometerThermo Scientific™ LC IsoLink™ IRMS SystemThermo Scientific™ Orbitrap Exploris™ 120 Mass SpectrometerThermo Scientific™ TSQ Quantis™ Triple Quadrupole Mass Spectrometer
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Catalog NumberIQLAAAGADIFZZZMZZZIQLAAEGAAPFALGMAZRIQLAAEGAATFAETMAHXIQLAAEGAAPFARBMBKQIQLAAEGAAXFZZZMZZZ
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Ionization Method(s)API, HESIInquireInquireInquireInquire
Mass AnalyzerSingle quadrupoleUHMR Hybrid Quadrupole-Orbitrap™InquireInquireInquire
Scanning SpeedUp to 20,000 Da/sec.up to 12 Hz at resolution setting of 12,500 at m/z 400InquireInquireInquire
ResolutionInquire200,000 at m/z 400InquireInquireInquire
DescriptionAdd mass spectrometry (MS) to your IC and LC analyses for access to the valuable data that only MS can provide. The new, easy-to-use Thermo Scientific™ ISQ™ EC Single Quadrupole Mass Spectrometer seamlessly integrates with ion chromatography (IC) and high performance liquid chromatography (HPLC) ... Read MoreThe Thermo Scientific™ Q Exactive™ UHMR Hybrid Quadrupole-Orbitrap™ mass spectrometer is the first to provide the unique combination of unprecedented ultra-high mass range resolution, highest sensitivity, and MS2 and pseudo-MS3 capabilities needed to go beyond what’s possible with today’s native MS ... Read MoreOpen new frontiers in isotope ratio mass spectrometry (IRMS) with the Thermo Scientific™ LC IsoLink™ IRMS System. By coupling HPLC and IRMS, the LC IsoLink IRMS System facilitates sensitive, accurate online determination of 13C/12C ratios for compounds that are either too volatile or thermally ... Read MoreThe Thermo Scientific Orbitrap Exploris 120 mass spectrometer accelerates your route to qualitative and quantitative confidence for both method development and everyday testing purposes. With its unique ability to provide consistently accurate data and a design made for operational simplicity, it ... Read MoreThe TSQ Quantis MS seamlessly integrates with industry-leading quantitation software, HPLCs and UHPLCs, and sample preparation solutions; it also offers enhanced efficiency during targeted quantitation workflows for a wide array of molecular species. Other benefits include:
  • Superb sensitivity that
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QuantityEAEAEAEAEA
TypeSeamless integration with IC or LCQuadrupole-Orbitrap LC-MSInquireMass SpectrometerInquire
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