LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ Orbitrap Exploris™ 480 Mass SpectrometerThermo Scientific™ Exactive™ Plus EMR Orbitrap™ LC-MS SystemThermo Scientific™ Orbitrap Eclipse™ Tribrid™ Mass SpectrometerThermo Scientific™ TSQ Quantis™ Triple Quadrupole Mass SpectrometerThermo Scientific™Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ LC-MS/MS Mass Spectrometer
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Catalog NumberIQLAAEGAAPFARBMBKRIQLAAEGAAPFALGMBDLIQLAAEGAAPFADBMBKSIQLAAEGAAXFZZZMZZZIQLAAEGAAPFALGMBDK
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Ionization Method(s)InquireAPCI, H-ESIInquireInquireAPCI, H-ESI
Mass AnalyzerInquireOrbitrapInquireInquireHybrid Quadrupole / Orbitrap
Scanning SpeedInquireUp to 12 HzOTMSn up to 40 Hz ITMSn up to 45 HzInquireUp to 12 Hz
Resolution480,000 at m/z 195up to 140,000 FWHM7500 to 500,000 (FWHM) at m/z 200Inquireup to 280,000 FWHM
DescriptionMaking genius simpler
Empowering life science researchers to translate each experimental step to a new level of insight with a next-generation ownership experience coupled with an intelligence-driven experimental approach. With the Thermo Scientific Orbitrap Exploris 480 mass spectrometer you'll
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While analysis of denatured proteins may be the most common LC/MS protein analysis, many biopharmaceutical and biological research applications require analysis of proteins in their native (intact) state. The Thermo Scientific™ Exactive™ Plus EMR mass spectrometer combines unsurpassed high-... Read MoreOne system, maximum insights
Today’s cutting-edge research pushes LC-MS to its limits. Obtaining high confidence insights to enable accurate resolution of subtle differences and avoid costly dead-ends is needed faster than ever before. The Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
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The TSQ Quantis MS seamlessly integrates with industry-leading quantitation software, HPLCs and UHPLCs, and sample preparation solutions; it also offers enhanced efficiency during targeted quantitation workflows for a wide array of molecular species. Other benefits include:
  • Superb sensitivity that
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Take Quanfirmation™ to the next level. The Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer introduced the revolutionary concept of Quanfirmation. The Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer takes Quanfirmation to the next level with increased ... Read More
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