LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ Orbitrap Eclipse™ Tribrid™ Mass SpectrometerQ Exactive™ UHMR Hybrid Quadrupole-Orbitrap™ Mass SpectrometerThermo Scientific™ ISQ™ EC Single Quadrupole Mass SpectrometerThermo Scientific™ Orbitrap Exploris™ 120 Mass SpectrometerThermo Scientific™ Orbitrap Exploris™ 240 Mass Spectrometer
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Catalog NumberIQLAAEGAAPFADBMBKSIQLAAEGAAPFALGMAZRIQLAAAGADIFZZZMZZZIQLAAEGAAPFARBMBKQIQLAAEGAAPFARBMBKP
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Ionization Method(s)InquireInquireAPI, HESIInquireInquire
Mass AnalyzerInquireUHMR Hybrid Quadrupole-Orbitrap™Single quadrupoleInquireInquire
Scanning SpeedOTMSn up to 40 Hz ITMSn up to 45 Hzup to 12 Hz at resolution setting of 12,500 at m/z 400Up to 20,000 Da/sec.InquireInquire
Resolution7500 to 500,000 (FWHM) at m/z 200200,000 at m/z 400InquireInquireInquire
DescriptionOne system, maximum insights
Today’s cutting-edge research pushes LC-MS to its limits. Obtaining high confidence insights to enable accurate resolution of subtle differences and avoid costly dead-ends is needed faster than ever before. The Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
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The Thermo Scientific™ Q Exactive™ UHMR Hybrid Quadrupole-Orbitrap™ mass spectrometer is the first to provide the unique combination of unprecedented ultra-high mass range resolution, highest sensitivity, and MS2 and pseudo-MS3 capabilities needed to go beyond what’s possible with today’s native MS ... Read MoreAdd mass spectrometry (MS) to your IC and LC analyses for access to the valuable data that only MS can provide. The new, easy-to-use Thermo Scientific™ ISQ™ EC Single Quadrupole Mass Spectrometer seamlessly integrates with ion chromatography (IC) and high performance liquid chromatography (HPLC) ... Read MoreThe Thermo Scientific Orbitrap Exploris 120 mass spectrometer accelerates your route to qualitative and quantitative confidence for both method development and everyday testing purposes. With its unique ability to provide consistently accurate data and a design made for operational simplicity, it ... Read MoreThe Thermo Scientific Orbitrap Exploris 240 mass spectrometer combines application flexibility with the performance to drive discovery and identification, plus receive the quantitative precision and accuracy you need to confidently scale up and achieve impact. With operational simplicity through ... Read More
QuantityEAEAEAEAEA
TypeInquireQuadrupole-Orbitrap LC-MSSeamless integration with IC or LCMass SpectrometerMass Spectrometer
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