Chemical ionization is a method used to ionize samples that will then be analyzed by mass spectrometry. Chemical ionization mass spectrometry is used in, among other industries, environmental science, the pharmaceutical industry, and research laboratories for quality control and research purposes. Negative chemical ionization (NCI) and positive chemical ionization (PCI) are two types of chemical ionization done to prepare for mass spectrometry. Most samples can make positive ions, but negative ions cannot be produced by any sample, so NCI is primarily used for samples that contain electronegative or acidic groups. Once ions are made from the samples, the mass spectrometer can measure their charge-to-mass ratio and provide an identifying spectrum.
Considerations for purchasing a Chemical Ionization Mass Spectrometer
Before purchasing a chemical ionization mass spectrometer, check the scanning rate, the size of the samples needed for analysis, the maximum sample size that can be handled, and which ionization method it uses.
Discover and compare Chemical Ionization Mass Spectrometers:
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| Company | Shimadzu | Shimadzu |
| Item | GCMS-TQ8040 NX Triple Quad GC/MS/MS | GCMS-QP2020 NX Gas Chromatograph Mass Spectrometer (GC/MS) |
| Citations | | |
| Catalog Number | GCMS-TQ8040 NX | GCMS-QP2020 NX |
| Price | | |
| Mass Analyzer | Quadrupole | Metal quadrupole with pre-rod |
| Ionization Method(s) | EI, CI, NCI | EI, CI, NCI |
| Description | Featuring Smart Productivity for high-efficiency sample throughput, Smart Operation for quick and easy method development, and Smart Performance for low detection limits and Scan/MRM, the GCMS-TQ8040 NX provides accurate, cost-effective and user-friendly triple quadrupole GC-MS/MS operation for Featuring Smart Productivity for high-efficiency sample throughput, Smart Operation for quick and easy method development, and Smart Performance for low detection limits and Scan/MRM, the GCMS-TQ8040 NX provides accurate, cost-effective and user-friendly triple quadrupole GC-MS/MS operation for routine analytical work.
Features: - Enables analysis of 400+ compounds in a single MRM run without sacrificing sensitivity or selectivity
- MRM Optimization Tool – seamlessly selects and optimizes MRM transitions for multiple compounds in a single sequence
- High-speed MRM analysis up to 800 transitions per second
- High-speed scanning control at 20,000 u/second
- Smart Database Series – provides fully automated method development at the touch of a button
- Smart MRM method creation protocol automatically sets the optimum dwell and loop times for each method to maximize sensitivity
- Flexible MS Events prevent losing compounds in the presence of a complex matrix
- Scan/MRM analysis mode simultaneously acquires accurate library-searchable mass spectra and low-level MRM quantitation in a single analysis
- Automatic Adjustment of Retention Times (AART) with > 99.9% accuracy means no need to adjust flow rates or update RTs manually
- Front-access ion source for quick, stress-free maintenance
This efficient design provides optimum performance in all analysis modes: MRM, SIM, Scan, Scan/MRM, Scan/SIM, Neutral Loss, Product Ion Scan, Precursor Ion Scan and combination modes.
The GCMS Smart Database Series simplifies GC-MS/MS method development. The series is comprised of separate databases for analyzing pesticides, forensic toxicological substances, metabolites and environmental pollutants. Each database includes hundreds of related compounds with optimized transitions and collision energies, CAS registry numbers and retention indices (RI). The software series supports simultaneous high-sensitivity analysis of samples using GC-MS/MS, eliminating the need to configure complicated analysis conditions.... Read More | Adopting a proprietary multi-function ion source and a new large-capacity turbomolecular pump with heightened exhaust efficiency for all carrier gases including nitrogen, the rugged, high-sensitivity GCMS-QP2020 NX elevates GCMS performance to a new level. New Quick-CI and Smart SIM functionality Adopting a proprietary multi-function ion source and a new large-capacity turbomolecular pump with heightened exhaust efficiency for all carrier gases including nitrogen, the rugged, high-sensitivity GCMS-QP2020 NX elevates GCMS performance to a new level. New Quick-CI and Smart SIM functionality reduces analysis times and running costs while front access to the ion source enables easier routine maintenance.
Features: - Smart SIM creation function – automatically creates a program that enables a staggered SIM of multiple components, resulting in higher SIM sensitivity
- Quick-CI function – allows users to introduce reagent gas while using the EI source to look for the molecular ion
- Advanced Scanning Speed Protocol – allows for the ability to scan up to 20,000 u/sec
- New turbomolecular pump achieves optimal performance with all carrier gases
- Front access to the ion source for easier, faster routine maintenance
- Simultaneous Scan/SIM for qualitative and quantitative data in a single run
- Twin-Line MS System – allows the GCMS-QP2020 NX to accept two narrow-bore capillary columns into the MS simultaneously, enabling users to switch applications without physically modifying the column installation
- Specialized databases with additional retention indices support more accurate qualitative analysis, convenient quantitative method development, and screening analysis.
Other features of the GCMS-QP2020 NX include a high-capacity differential vacuum system; high-sensitivity ion source; high-performance quadrupole mass filter; and easy sTop, which enables users to perform maintenance on the injection port without venting the MS, for drastic reduction of maintenance time.
GCMSsolution software provides intuitive control of the GCMS-QP2020 NX. Also available is LabSolutions Insight. This data review software enables faster quantitative analysis and higher productivity when analyzing pesticides, forensic toxicological substances, environmental pollutants, and many other substances. In addition, each system can be configured with a variety of sample introduction devices to address specific application requirements.... Read More |
| Mass Range | Inquire | 1.5 to 1090 m/z |
| Scanning Speed | 20,000 u/sec | 20,000 u/sec |
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