The analysis of ion channels in membranes, and the ability to inject genes into cells, all require a steady grip that no human hand can supply. Micromanipulators allow the scientist or clinician to accomplish microinjection, patch clamp experiments, extracellular and intra-cellular recordings or precision robotics by carefully controlling microelectrode and syringe movement and capillary flow. Micro-step motors ensure precise movements in three – or even four – dimensions, with resolutions as high as 0.0625 um/step. Stop locks and extra springs ensure minimal drift along the four axes. Some micromanipulator platforms provide central control over four simultaneous manipulators. Though mostly geared toward biochemical applications, a micromanipulator also has uses in micro-electronics and material science. These models tend to have higher thermal and mechanical stability.
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Company | Sutter Instrument | Sutter Instrument | Sutter Instrument |
Item | MP-225A Motorized Micromanipulator | MP-85 Huxley Wall Type Micromanipulator | QUAD® 4-Axis Motorized Micromanipulator |
Citations | | | |
Catalog Number | MP-225A | MP-85/R,/L | QUAD-L/R |
Price | | | |
Full Travel | 25 mm each axis (1 in) | ~2 mm on each axis | Inquire |
Resolution | 0.0625, 0.125, 0.25, 0.5, 1.0 and 2.0 um/step | 0.1 mm (Coarse), 0.01 mm (Fine), 0.2 µm (Ultrafine) | Inquire |
Max. Speed | 2.0 mm/sec | Inquire | Inquire |
Drift | Inquire | Inquire | Inquire |
Drive Mechanism | Integral Miniature Stepper Motor Anti-Backlash Gearhead | Inquire | Inquire |
Description | The MP-225 is one of the newer members in the Sutter Instrument micromanipulator line. Production and design changes have allowed us to produce a motorized manipulator that is a more affordable alternative to the industry standard MP-285. While the MP-225 feature set is less comprehensive than the The MP-225 is one of the newer members in the Sutter Instrument micromanipulator line. Production and design changes have allowed us to produce a motorized manipulator that is a more affordable alternative to the industry standard MP-285. While the MP-225 feature set is less comprehensive than the MP-285, it includes the most popular features with a user interface that is simpler to use. The mechanical design utilizes a miniature stepper motor and integral anti-backlash gear head. Pre-loaded ball bearing slides provide smooth movement throughout the 25mm of travel. The controller uses low-noise, linear-drive output circuitry identical to that found in the MP-285. The methodology for mounting pipette holders and headstages used with the MP-285 has been maintained in the MP-225 to allow for cross compatibility.
The MP-225 is designed primarily for positioning patch and intracellular recording pipettes. We have retained and refined the features most desired for this type of work. An extended version of the popular rotary optical encoder (ROE) is the sole input device available with the MP-225. Like the MP-285, the manipulator has a synthetic 4th axis for diagonal advancement of the pipette; 16 different angles are selectable via DIP switches. Speed and resolution of movement are easily selected with a multiple position thumbwheel, allowing fast/coarse movement and slow/ultra-fine movement in 10 increments. Two commonly used robotic movements have been incorporated for user convenience. A single button press can initiate a move to a Home position for pipette exchange or to a user defined Work position for quick location of the pipette near the recording location.
A display on the ROE gives position location. As all controls are located on the ROE, the controller can be moved to a less accessible area of your setup and does not need to occupy prime space in an equipment rack.
As always, our technical support team is available to address your particular needs and answer all questions before and after your purchase.
Features: MP-225
- Highly stable for experiments intolerant of pipette drift.
- Submicron (62.5nm) minimal resolution for fine movement.
- Convenient thumbwheel selects resolution/speed of movement.
- 25mm of motorized travel on all three axes.
- 4th axis for coaxial movement of pipette, angle selected by DIP switches on ROE.
- ROE button press actuates move to Home position for pipette exchange.
- ROE button press actuates move to Work position near recording location.
- Continuous display (in microns) of axes positions located on ROE.
- DIP switches on ROE select direction of movement produced by turn of ROE knob.
- Modularized, compact design easily adaptable to your setup.
- Mounting adapters included with manipulator.
... Read More | The classic micromanipulator developed by Sir Huxley many years ago is still considered by many investigators to be the finest manual micromanipulator available. The MP-85 offers the advantage of a very large range of movement with its built-in coarse manipulator and precise submicron movement with The classic micromanipulator developed by Sir Huxley many years ago is still considered by many investigators to be the finest manual micromanipulator available. The MP-85 offers the advantage of a very large range of movement with its built-in coarse manipulator and precise submicron movement with the fine controls. Coarse positioning is achieved with a three axis manipulator mounted on top. The ultrafine positioning is accomplished with the large micrometers mounted on the base. These micrometers provide smooth, precise movement through a 10:1 reduction mechanism.
The brass and stainless steel construction of the MP-85 makes for a very heavy and solid micromanipulator with excellent damping properties. This exceptionally stable design is ideal for patch clamp recording, intracellular recording, or any other application that is intolerant of drift.
Please contact Sutter Instrument for any additional information on the suitability and use of the MP-85 micromanipulator for your specific application. Features: MP-85 Dual springing of the moment arms to insure zero backlash and zero torsion. The micromanipulator is mounted on a precision rotating base featuring a positive stop and lock. The coarse movement is an all cross-roller bearing design consisting of coarse X, Y, and Z with an additional fine X motion. The micromanipulator can be ordered in either a right or left handed version.
Options: MP-85 Fifteen degree stackable wedges for tilting the manipulator. A set of three magnetic feet for increased stability. One inch thick, chrome plated, solid brass riser blocks. The MP-85 is chrome-plated and anodized to prevent corrosion. The J.R. Wall designed rotating base is machined from solid stainless steel with a brass spindle; a thin Teflon washer provides for the bearing surface. ... Read More | The QUAD® motorized micromanipulator is easy to use and features four independent axes. Each axis has a 25mm range of motion, a digital display of position and an ROE control. The compact, intuitive controller takes up minimal bench space, is fan free and is easy to use. Three axes provide the X, Y,The QUAD® motorized micromanipulator is easy to use and features four independent axes. Each axis has a 25mm range of motion, a digital display of position and an ROE control. The compact, intuitive controller takes up minimal bench space, is fan free and is easy to use. Three axes provide the X, Y, Z-orthogonal motion typical of most motorized micromanipulators. In the QUAD, Sutter introduces a true fourth axis to move the electrode coaxially at exactly the desired angle of approach. The fourth axis has 30mm of travel that significantly extends the range of travel for the system.
Features:- Four independent axes - 30mm travel in diagonal for coaxial pipette movement, 25mm travel in X, Y and Z
- Sub-micron 100nm resolution
- True diagonal assures coaxial movement
- Quiet mode eliminates electrical noise
- Display indicates coordinates in relative or absolute
- User-friendly, fanless compact controller with ROE preserves bench space
- Push button control of multiple functions - WORK, HOME, LOCK, PULSE and RELATIVE
- Robotic HOME and WORK position moves for easy automated pipette exchange
- Suited for in vivo electrophysiological recording
- USB interface for computer control
... Read More |
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