The analysis of ion channels in membranes, and the ability to inject genes into cells, all require a steady grip that no human hand can supply. Micromanipulators allow the scientist or clinician to accomplish microinjection, patch clamp experiments, extracellular and intra-cellular recordings or precision robotics by carefully controlling microelectrode and syringe movement and capillary flow. Micro-step motors ensure precise movements in three – or even four – dimensions, with resolutions as high as 0.0625 um/step. Stop locks and extra springs ensure minimal drift along the four axes. Some micromanipulator platforms provide central control over four simultaneous manipulators. Though mostly geared toward biochemical applications, a micromanipulator also has uses in micro-electronics and material science. These models tend to have higher thermal and mechanical stability.
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| Company | Sutter Instrument | Sutter Instrument | Sutter Instrument |
| Item | MM-33 / MM-33A Micromanipulator | MP-85 Huxley Wall Type Micromanipulator | MPC-385 Multi-Manipulator Controller and ROE-200 |
| Citations | | | |
| Catalog Number | MM-33/R,/L,MM-33-A/R,/L | MP-85/R,/L | MPC-385/-2/-3/-4 |
| Price | | | |
| Full Travel | Inquire | ~2 mm on each axis | 25 mm each axis |
| Resolution | 5 µm | 0.1 mm (Coarse), 0.01 mm (Fine), 0.2 µm (Ultrafine) | Min. Microstep Size = 62.5 nm |
| Max. Speed | Inquire | Inquire | 3 to 5 mm/sec (depending on model) |
| Drift | Inquire | Inquire | less than 1 micron/hr |
| Drive Mechanism | Inquire | Inquire | Inquire |
| Description | Used in complex experiments in conjunction with our other micromanipulators, or as a stand alone unit in a teaching environment, the MM-33 is available separately for those wishing a small, practical instrument in applications not requiring submicron accuracy.
The MM-33 is the right choice for Used in complex experiments in conjunction with our other micromanipulators, or as a stand alone unit in a teaching environment, the MM-33 is available separately for those wishing a small, practical instrument in applications not requiring submicron accuracy.
The MM-33 is the right choice for tight environments which require maximum versatility within a small space. The optional rotating base and tiltable X-axis provide even further flexibility.
Stainless steel cross-loaded roller bearings are designed to offer low friction and smooth linear motion with a minimum of side play. The pre-loaded rollers are set at 90 degrees to the hardened steel guides ensuring constant contact and accuracy. This precise rack and pinion drive gives stable, drift free movement with minimal backlash. The controls are placed one above the other which makes for less hand movement and easier positioning. The scales for all axes are calibrated in 0.10mm increments and the fine micrometer adjustment for the X-axis thrust is calibrated at 0.01mm with estimates to 5µm.
The optional rotating base extends the utility of the MM-33 by providing two additional rotating planes. The rotation in the horizontal plane (approximately 120 degrees) has a positive stop, quick release mechanism for fast insertion and removal of pipettes. The second rotating axis allows the MM-33 to be tilted in a vertical plane from 0 to 70 degrees.
The optional tiltable X-axis allows the fine axis to be tilted up to 45 degrees. An optional vertical lock is also available for locking the position of the vertical axis. These options should be ordered at the time of purchase since the modifications are factory installed.
Individual excursions are as follows:
X-axis coarse movement: 37mm
X-axis fine movement: 10mm
Y-axis horizontal movement: 20mm
Z-axis vertical movement: 20mm Features: MM-33
Compact design allows use in tight environments.
Cross-loaded roller bearings for smooth, low friction movement.
Rack and pinion drive gives stable movement with minimal backlash.
Options: MM-33A
Rotating base allows horizontal rotation and vertical tilting.
Rotating base allows horizontal rotation and vertical tilting.
Vertical axis lock. ... Read More | The classic micromanipulator developed by Sir Huxley many years ago is still considered by many investigators to be the finest manual micromanipulator available. The MP-85 offers the advantage of a very large range of movement with its built-in coarse manipulator and precise submicron movement with The classic micromanipulator developed by Sir Huxley many years ago is still considered by many investigators to be the finest manual micromanipulator available. The MP-85 offers the advantage of a very large range of movement with its built-in coarse manipulator and precise submicron movement with the fine controls. Coarse positioning is achieved with a three axis manipulator mounted on top. The ultrafine positioning is accomplished with the large micrometers mounted on the base. These micrometers provide smooth, precise movement through a 10:1 reduction mechanism.
The brass and stainless steel construction of the MP-85 makes for a very heavy and solid micromanipulator with excellent damping properties. This exceptionally stable design is ideal for patch clamp recording, intracellular recording, or any other application that is intolerant of drift.
Please contact Sutter Instrument for any additional information on the suitability and use of the MP-85 micromanipulator for your specific application. Features: MP-85
Dual springing of the moment arms to insure zero backlash and zero torsion.
The micromanipulator is mounted on a precision rotating base featuring a positive stop and lock.
The coarse movement is an all cross-roller bearing design consisting of coarse X, Y, and Z with an additional fine X motion.
The micromanipulator can be ordered in either a right or left handed version.
Options: MP-85
Fifteen degree stackable wedges for tilting the manipulator.
A set of three magnetic feet for increased stability.
One inch thick, chrome plated, solid brass riser blocks.
The MP-85 is chrome-plated and anodized to prevent corrosion. The J.R. Wall designed rotating base is machined from solid stainless steel with a brass spindle; a thin Teflon washer provides for the bearing surface. ... Read More | Neurobiological experiments are becoming more complex. Many require multiple manipulators with control units that quickly become space and/or cost prohibitive. The MPC-200 is the solution you have been asking for. A single controller capable of running 2 manipulators! Sutter Instrument has taken the Neurobiological experiments are becoming more complex. Many require multiple manipulators with control units that quickly become space and/or cost prohibitive. The MPC-200 is the solution you have been asking for. A single controller capable of running 2 manipulators! Sutter Instrument has taken the simplicity of the MP-225 controller and expanded it to run two manipulators from a single controller/ROE. The MPC-200 works with one or two of our world-renowned mechanicals, the MP-285 (MPC-385), the MP-225 (MPC-325) or the narrow format MP-265 (MPC-365). The controller is self-detecting so there is no need for manual configuration of the components.
If two manipulators aren't enough, a second controller can be daisy chained to allow the single ROE-200 to move up to four manipulators. Thus the system can be easily expanded to control highly sophisticated experiments.
The Sutter MPC-200 is electrically quiet. Unlike the competition, our multi-unit controller employs linear output circuitry. Sutter adds additional manipulators to the same controller without requiring potentially noisy chopper drives.
Faster automated pipette exchange. The MPC-200 has faster “Home” and “Work Position” moves for quicker pipette exchange. Automation is set up and run via the same interface used in the MP-225 controller; however, the speeds of the automated movement are much faster.
Accelerated manual mode. For users who prefer manual pipette exchange we have added “Accelerated Mode” to the ROE. Using Accelerated Mode, the user can make quick manual moves in and out of a setup. Accelerated Mode amplifies the speed attainable in a manual move by smoothly accelerating to the maximum speed during sustained, fast turns of the ROE. Accelerated movement ends as soon as the user stops turning the knob. This mode can be fully disabled for those who feel the need for direct control of the pipette.
To provide the ultimate in flexibility, the MPC-200 can be purchased separately or in one of several basic systems such as the MP-385 or the MP-325. Additional component pieces can be added at any time, allowing the user to develop a system tailored to his or her particular needs. Features: MPC-200 and ROE-200 - Single controller and ROE will run two stepper motor drive manipulators
- Self-detecting, daisy-chain capability allows control of four manipulators from one ROE-200
- User-friendly interface: single button access to all major functions
- New Accelerated Mode for fast, manual manipulator movement
- Easy toggle selection of Mode (speed/resolution, pulsed diagonal, Accelerated Mode)
- Display indicates X, Y, Z coordinates, Mode, active manipulator
- Robotic Home and Work Position moves for easy automated pipette exchange
- Faster robotic moves than previous versions
- Definable 4th axis for coaxial pipette movement, angle selected by DIP switches
- Simple USB interface
- Toggle switch selects which manipulator is connected to input device
- LED and display indicate active manipulator
- Low-drift mechanical stability
... Read More |
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