Numerous bodily processes possess the ability to produce detectable electrical signals. Distinct methodologies and techniques exist in order to accurately target these signals, depending on their locations and sources. Electrophysiology equipment is vast and includes instruments such as patch-clamp amplifiers, ion channel readers, ECG and EKG machines, and many more. With applications in optogenetics, clinical diagnostics, and molecular and cellular labs, to name only a few, electrophysiology can study the electrical properties of tissues and cells.
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| Company | Molecular Devices, LLC | Molecular Devices, LLC | Molecular Devices, LLC |
| Item | Axon Instruments Patch-Clamp Amplifiers | Axon Digidata 1550 System | IonWorks Barracuda system |
| Catalog Number | Axon Patch-Clamp Amplifiers | Inquire | Inquire |
| Price | | | |
| Description | Patch-clamp amplifiers from single channels to large macroscopic recordings
The Axon Instruments® series of amplifiers provide best-in-class solutions for the entire range of patch-clamp experiments. The portfolio of amplifiers includes Axopatch™ 200B for ultra low-noise single-channel recordings, Patch-clamp amplifiers from single channels to large macroscopic recordings
The Axon Instruments® series of amplifiers provide best-in-class solutions for the entire range of patch-clamp experiments. The portfolio of amplifiers includes Axopatch™ 200B for ultra low-noise single-channel recordings, MultiClamp™ 700B for whole-cell voltage-clamp and high-speed current-clamp recordings, and Axoclamp™ 900A for two-electrode voltage-clamp and current-clamp recordings.
Actively cooled headstage -
The Axopatch 200B amplifier features proprietary technology that provides active headstage cooling that reduces electrical noise close to the theoretical limits of physics.
Software control of settings -
The MultiClamp 700B and Axoclamp 900A amplifiers offer software control. Software control streamlines setup, and enables automation of parameters, telegraphing, and advanced protocols.
Support up to four headstages -
The MultiClamp 700B supports up to two primary CV-7B headstages and two optional auxiliary headstages (HS-2 or VG-2 type) enabling multi-channel recording for cellular network studies.
Large output compliance range -
The Axoclamp 900A amplifier supports the measurement of larger currents and ensures faster clamp speed (±180 V in TEVC and HVIC modes).
Multiple modes of operation -
The Axoclamp 900A amplifier offers 5 modes of operation: current clamp, discontinuous current clamp, two-electrode voltage clamp, discontinuous single-electrode voltage clamp, high-voltage current clamp.
Works with any data acquisition system -
The family of amplifiers integrates with most data acquisition programs. The pCLAMP™ 11 Software and DigiData® 1550B system for data acquisition and analysis provide optimal performance.
Other features and benefits include - - Minimize signal to noise ratio
- Preform multi-channel experiments
- Measure large currents
... Read More | The Axon™ Digidata® System is the most widely used for a variety of electrophysiology recordings in laboratories worldwide. This Digidata 1550 Digitizer further extends the precision and quality of the existing Axon Digitizer platform with enhanced performance in command voltage output control and The Axon™ Digidata® System is the most widely used for a variety of electrophysiology recordings in laboratories worldwide. This Digidata 1550 Digitizer further extends the precision and quality of the existing Axon Digitizer platform with enhanced performance in command voltage output control and sampling rate. It enables to record up to 8 cells simultaneously to study the function of neuronal networks in your neuroscience research. It also achieves a high-resolution data acquisition by capturing more data point in less time in your ion channel research.
Features - 8 analog input channels to digitize acquired signals up to 500 kHz independently
- 8 analog output channels to send command voltage output independently
- 8 digital out channels to control the periphery equipment used in sophisticated experiments
- Independent analog-to-digital converters for each input channel ensure low crosstalk levels and high data acquisition rates.
- USB 2.0 connection allows operation on virtually any current PC computer running Microsoft Windows 7 (32-bit or 64-bit) Operating System, including laptops.
- 16-bit resolution for state-of-the-art signal-to-noise ratio All signal connectors on the front panel for ease of access and maintenance of the electrophysiology setup
- Rack-mount case for tidy installation of all components in the electrophysiology set-up
- User guide written by scientific consultants, with the assistance of Axon Instruments staff, for straightforward start-up and as an in-depth reference.
... Read More | IonWorks® systems are the most widely used automated electrophysiology platforms in laboratories worldwide. The next generation IonWorks Barracuda® system provides an affordable, rapid solution for high-throughput primary screens of mid-to-large compound libraries as well as compound profiling and IonWorks® systems are the most widely used automated electrophysiology platforms in laboratories worldwide. The next generation IonWorks Barracuda® system provides an affordable, rapid solution for high-throughput primary screens of mid-to-large compound libraries as well as compound profiling and early safety screens.
Features - Studies show that mega-seal recordings give comparable results to giga-seal for most channels
- Highest throughput available
- Unmatched flexiblity for assay support and development
- Automation solutions for walk-away operation up to six hours
... Read More |
| Type | Inquire | Inquire | Automated |
| Applications | Inquire | Basic Ion Channel Research, Cell Pathway Analysis, Disease Research, Safety Assessment | Primary screening of directed libraries, Rapid lead identification, Flexibility to optimize leads and perform safety studies, Clonal selection |
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