In Raman microscopy, also called confocal Raman microscopy, an optical microscope and a Raman spectrometer are combined into one instrument in order to provide high resolution images of small samples. This high resolution imaging has applications that include materials science, earth science, cell biology, medicine, cosmetics, and art analysis.
A Raman microscope consists of a basic optical microscope, a Raman spectrometer, a laser, a light source, and a detector such as a CCD camera. The optical microscope uses light to magnify and identify samples while the Raman spectrometer scatters light and measures the excitation vibration. When selecting a microscope, it is important to consider the qualities of each of the microscope's components and their optimal configuration for a particular application.
Find, compare, and request a quote for Raman and confocal Raman microscopes across leading suppliers at Labcompare; including access to product citations, related published figures, and first-hand reviews from our scientific community.
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| Company | Oxford Instruments | Oxford Instruments | Oxford Instruments | Oxford Instruments |
| Item | witec360 Raman Microscope | Hexalight – Raman Spectrometer | ParticleScout – Raman-based Particle Analysis | RISE Microscopy – Raman Imaging-SEM |
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| Catalog Number | witec360 | | ParticleScout™ | RISE™ Microscopy |
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| Description | The witec360 Raman microscope features all the performance and versatility of the WITec alpha300 series while enhancing light transmission and automation, and encompassing standard and inverted beam versions, dedicated and correlative configurations, and systems with varying levels of automation.
The witec360 Raman microscope features all the performance and versatility of the WITec alpha300 series while enhancing light transmission and automation, and encompassing standard and inverted beam versions, dedicated and correlative configurations, and systems with varying levels of automation.
The Hexalight spectrometer offers unprecedented throughput from 350 to 1100 nanometres and a revolutionary harmonic drive that positions up to six gratings with a new degree of precision. With the witec360 Raman microscope, it constitutes the most advanced confocal Raman imaging system yet devised.
Researchers from principal investigators to industry scientists and core lab managers can benefit from the witec360.... Read More | Hexalight is the groundbreaking spectrometer at the core of witec360 Raman microscopes. It establishes new standards in throughput and spectral flexibility by incorporating an innovative lens-based, mirror-free design and providing unprecedented broadband capabilities.
Engineered for the needs of Hexalight is the groundbreaking spectrometer at the core of witec360 Raman microscopes. It establishes new standards in throughput and spectral flexibility by incorporating an innovative lens-based, mirror-free design and providing unprecedented broadband capabilities.
Engineered for the needs of advanced research and development, Hexalight delivers exceptional performance across the spectrum, making it ideal for multi-user environments by accommodating diverse applications within a single device. Its modular setup ensures long-term scalability to adapt to evolving needs and budgetary conditions.
- Broadband capability Achieve top-tier optical performance across a wide spectral range (350 – 1100 nm).
- Scalable architecture Easily adapt to future experimental needs with six grating positions for cost-efficient upgrades.
- Streamlined operation Simplify handling and protect grating integrity with software-controlled grating selection for increased system uptime, longevity and user convenience.
- Trustable, reproducible results Ensure the highest image accuracy and consistent, distortion-free results with ultra-precise automated grating positioning and the OHD lens-based optics.
- Exceptional signal sensitivity Use reduced laser power for sensitive samples and to detect even the faintest Raman signals via Hexalight’s mirror-free beam path and ultra-sensitive CCD cameras that maximize the signal intensity.
- High-speed data acquisition Accelerate workflows and reduce integration times through Hexalight’s outstanding sensitivity.
... Read More | ParticleScout is an advanced particle analysis tool for witec360 Raman microscopes that finds, classifies and identifies microparticles over even large sample areas.
User-defined categorization of particles by shape and size offers access to wide-ranging properties, and the results of the ParticleScout is an advanced particle analysis tool for witec360 Raman microscopes that finds, classifies and identifies microparticles over even large sample areas.
User-defined categorization of particles by shape and size offers access to wide-ranging properties, and the results of the measurement are then presented in a report that provides a comprehensive description of the sample.
ParticleScout features the most flexible and useful sample survey capabilities available.
- White-light Microscopy: Bright field/dark field, transmission/reflection.
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Image Stitching: Scans of many sample areas can be combined into one measurement for a large-area overview of widely distributed particles.
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Focus Stacking: This unique capability dramatically increases the depth of focus for sharp and defined particle imaging.
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Integration time optimisation – reduces measurement time and minimizes the effects of fluorescence.
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Vignetting correction – ensures uniform brightness throughout the image plane.
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Smart zoom – displays particle information dynamically depending on viewed area.
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Sample area targeting – allows the selection of multiple regions of interest for each investigation.
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Dark-field, bright-field, epifluorescence and transmission sample illumination – provides the best option for each type of particle.
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Round sample wedge sectioning – allows the selection of an area for data acquisition, typically on a filter, that can be extrapolated to represent the whole.
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Smart separation of particles – differentiates materials in densely packed, heterogeneous samples.
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• Quantitative report formatting – presents data using table, bar graph histogram and pie chart templates for ease and clarity.
... Read More | RISE Microscopy is a novel correlative microscopy technique that combines confocal Raman Imaging and SEM to link ultra-structural surface properties with molecular compound information.
The RISE Microscope combines all features of a stand-alone SEM and the witec360 confocal Raman imaging microscopeRISE Microscopy is a novel correlative microscopy technique that combines confocal Raman Imaging and SEM to link ultra-structural surface properties with molecular compound information.
The RISE Microscope combines all features of a stand-alone SEM and the witec360 confocal Raman imaging microscope within one instrument.
- Quick and convenient switching between Raman and SEM measurement.
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Automated sample transfer from one measuring position to the other.
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Integrated software interface for user-friendly measurement control.
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Correlation of the measurement results and image overlay.
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No compromise in SEM and Raman imaging capabilities.
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| Measurement Mode(s) | Confocal Raman Imaging Microscopy | Confocal Raman Imaging Microscopy | Raman-based particle analysis | Raman Imaging-SEM |
| Detector(s) | CCD/EMCCD | CCD/EMCCD | CCD/EMCCD | CCD/EMCCD |
| Laser Sources | Multiple Laser Sources | Single Laser Source | Multiple Laser Sources | Multiple Laser Sources (up to six) |
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