An HPLC detector is used to analyze the components of the eluted mixture that is collected after being run through an HPLC column. Differences in detector type are based on what is being detected. Detection can be done by measuring absorbance, changes in reflex indices, molecular weight, and fluorescence among others. When selecting a detector, it is important to consider the sample type being analyzed. Some sample types will not work or will have lower sensitivity on particular detectors. Also of consideration is the type of information that is being sought by the analysis and what method will be used when running the column, for example, some detectors will work with the gradient method while others will not.
Find, compare, and request a quote for HPLC detectors across leading suppliers at Labcompare; including access to product citations, related published figures, and first-hand reviews from our scientific community.
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| Company | Shimadzu | Shimadzu | Shimadzu | Shimadzu |
| Item | CDD-10Avp HPLC Conductivity Detector | ELSD-LTIII Low Temperature Evaporative Light Scattering Detector | RID-20A Refractive Index Detector | SPD-M40 HPLC/UHPLC Photodiode Array Detector |
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| Catalog Number | CDD-10Avp | ELSD-LTIII | RID-20A | SPD-M40 |
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| Type | Conductivity Detector | Low Temperature ELSD | High-Sensitivity Refractive Index Detector | Photodiode Array Detector |
| Detector(s) | Inquire | Photodiode | High-Sensitivity Refractive Index Detector | Photodiode Array |
| Applications | Environmental, water testing, and food laboratories. | General-purpose universal detector that can even detect components with no UV absorption, such as carbohydrates, lipids, surfactants, and synthetic polymers (excluding some volatile compounds). | Inquire | Inquire |
| Description | Experience reliable, user-friendly, versatile, and high sensitivity ion chromatography (IC) detection for environmental, water testing, and food laboratories. With its wide dynamic rage, the CDD-10AVP conductivity detector assures minimal noise and drift. This versatile high sensitivity conductivityExperience reliable, user-friendly, versatile, and high sensitivity ion chromatography (IC) detection for environmental, water testing, and food laboratories. With its wide dynamic rage, the CDD-10AVP conductivity detector assures minimal noise and drift. This versatile high sensitivity conductivity detector is intended for a non-suppressed system.
- Small cell volume of 0.25µL.
- Low noise (< 4 nS/cm) and low drift (< 25 nS/cm/h) for high sensitivity analysis.
- Maximum cell pressure of 2.9MPa (29 bar).
- Wide operating temperature range (4 to 35°C) and cell temperature control range from 25 to 55°C.
- Tine constant settings from 0.05 to 10 sec.
- In-run autozero and correction of baseline shifting is possible.
... Read More | Capable of highly sensitive detection of non-chromophoric components, the ELSD-LT III evaporative light scattering detector meets a wide range of needs such as impurity analysis and comprehensive detection. In addition, it can detect semi-volatile compounds and heat-labile compounds with high Capable of highly sensitive detection of non-chromophoric components, the ELSD-LT III evaporative light scattering detector meets a wide range of needs such as impurity analysis and comprehensive detection. In addition, it can detect semi-volatile compounds and heat-labile compounds with high sensitivity, and be used as a detector for preparative LC.
Key features and benefits:
- Uses a high-power semiconductor laser as the light source, which enables sensitivity approximately 10 times higher than that of conventional products – the highest level of sensitivity for an ELSD.
- Achieves a wide dynamic range of 5 orders of magnitude, providing simultaneous determination of high-concentration and trace components without gain switching. This eliminates the need for dilution/preparation of samples, cumbersome sensitivity settings, and the waste of samples due to failure to set sensitivity when considering methods.
- “Temperature ready” function ensures the reliability of the data because it executes analysis after confirming that the temperature of the drift tube has reached the set temperature. This function detects a decrease in gas pressure and stops the system with an error.
- Compact design reduces instrument height by 30% compared to conventional products, so it can be installed on the column oven, saving installation space.
... Read More | The cost-effective, easy-to-use RID-20A refractive index detector is equipped with a dual temperature control structure for the optical system and flow cell. A modified thermal design provides excellent baseline stability and shorter initial stabilization time.
Key features include:The cost-effective, easy-to-use RID-20A refractive index detector is equipped with a dual temperature control structure for the optical system and flow cell. A modified thermal design provides excellent baseline stability and shorter initial stabilization time.
Key features include:
- Measurement range of 1 to 1.75 RIU
- Noise ≤ 2.5 x 10-9 RIU and Drift ≤ 1 x 10-7 RIU/h.
- Shorter baseline stabilization time after turning ON the power
- Reference-cell auto-purge feature and validation support function
- Reduced consumption of mobile phase
- Wide refractive index range (0.01 to 5000 µRIU) with four-partition photodetector
... Read More | The SPD-M40 has great accuracy in identification of compounds from absorbance spectra and performs an impurity check on all peaks. The industry leading i-PDeA deconvolution algorithm spectrally resolves coeluting peaks. The newly designed optical system guarantees both a wide linearity range and a The SPD-M40 has great accuracy in identification of compounds from absorbance spectra and performs an impurity check on all peaks. The industry leading i-PDeA deconvolution algorithm spectrally resolves coeluting peaks. The newly designed optical system guarantees both a wide linearity range and a superb signal-to-noise ratio performance at the same time. It has improved stability in analysis through flow cell/polychromator/lamp compartment temperature control. Each SPD-M40 is equipped with a UV cutoff filter, which allows even less variation and more robust analysis by minimizing sample decomposition.
Features:
- Wavelength range of 190 nm - 800 nm, wavelength accuracy ± 1 nm, noise level of 4.5 x 10-6 AU, and drift less than 0.4 x 10-3 AU/hour.
- UV cut-off filter that removes wavelengths below 240 nm from entering the flow cell.
- Has a 1024 element diode array. Fully temperature-controlled optics, including the optical bench, lamp housing, and flow cell. Monitored and controlled with a standard web browser.
- Built-in Cell ID that is automatically recorded in analysis data.
- Linear up to 2.5 AU (ASTM method). Pressure tolerance of 12 MPa.
- Automatic wavelength accuracy check and wavelength correction.
- Integrated 4 channel analog output.
- Capable of using the i-PDeA II deconvolution algorithm to resolve co-eluting peaks.
... Read More |
| Wavelength Range | NA | NA | Inquire | 190 to 800 nm |
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