Mass spectrometry uses molecular weight measurement to provide invaluable information on a molecule’s mass, structure, and chemical properties. MS can identify unknown materials and quantify known compounds. Mass spectrometry systems are often integrated with other separation techniques, including GC, LC, and UHPLC.
How Does Mass Spectrometry Work?
Basic mass spectrometry configurations share a common theme: Sample molecules are introduced into the sample inlet and an ion source converts the molecules to ions, or charges them. Common ionization techniques include electron and chemical ionization for gases and vapors, ESI and MALDI for liquids and solids, and ICP for cation analysis.
Next in line is the mass analyzer, which separates the ions according to their m/z. Mass analyzer types include quadrupole, ion trap, time of flight, and quad TOF. An ion detector such as an electron multiplier produces the final mass spectrum.
What is Mass Spectrometry Used For?
A few applications of this powerful analytical technique:
Determining protein structure in proteomics and drug structure in drug discovery
Detecting drugs of abuse in clinical testing
Identifying water or food contamination in environmental testing.
Search and Compare Mass Spectrometry Solutions for your Lab
The 7000C Triple Quadrupole GC/MS was designed to deliver ... read more
The Agilent 8800 ICP Triple Quad (ICP-QQQ) is a unique ... read more
Forensic laboratories face the need to analyze many samples of human blood and body fluids for ... read more
Solid phase extraction (SPE) is a liquid chromatography method of separating a particular compound, ... read more
Tecan’s AC Extraction Plate reduces LC-MS sample preparation to a simple pipetting and shaking routine. Three easy steps of extraction, wash and elution require no centrifugation, filtration or evaporation. This plate allows for easy transition of ...
Sigma Aldrich introduces Supel QuE Z-Sep sorbents for QuEChERs. QuEChERs is a solid phase extraction (SPE) technique for sample preparation.
Monday, February 24, 2014
Markes International (Llantrisant, UK), a leading innovator and manufacturer of technology for trace organic analysis, has announced the launch of its new website read more
Monday, February 24, 2014
Markes International (Llantrisant, UK), a leading innovator and manufacturer of technology for trace organic analysis, has announced that it will be showcasing its new Select-eV technology for gas chromatography–mass spectrometry for the first time in North America on its booth (#1519) at Pittcon ... read more
Tuesday, January 28, 2014
Markes International (Llantrisant, UK), a world leader in instrumentation for trace organic analysis, has announced the launch of a variable-energy electron ionisation source technology for GC–MS, Select-eV®. read more
Participating at a variety of levels and focused on the productivity and elegance of automated research, Beckman Coulter Life Sciences will be presenting workshops and posters and have a dynamic, interactive booth (#605) at this year’s meeting of the Society for Laboratory Automation and Screening (... read more
Thursday, December 26, 2013
The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, a Pennsylvania non-profit corporation, is proud to announce its 2014 Pittsburgh Conference Memorial National College Grant (PCMNCG) recipients. read more