Ultra High Performance Liquid Chromatograph (UHPLC)

Ultra high-performance liquid chromatography, UHPLC, uses columns packed with porous sub-2-µm particles (usually 1.8 µm) to vastly increase throughput and resolving power compared to conventional 5-µm columns. Pressures can surpass 19,000 psi. Limited solvent consumption, the ability to work under a broader pressure range, and lower band broadening are further enhancements. UHPLC’s 10× reduction in analysis time strengthens its popularity in areas including the pharmaceutical industry, food safety, and the clinical field. The choice of detectors for use with UHPLC is wide-ranging, including UV-VIS, fluorescence, photodiode array, ELSD, quadrupole, and most recently, refractive index. For flexibility, many instruments offer the ability to run both conventional and UHPLC on one instrument. A final tip: When making the switch from HPLC to UHPLC, resist the temptation to overload the smaller columns.

Discover and compare Ultra High Performance Liquid Chromatographs:

CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ Vanquish™ Duo UHPLC SystemsThermo Scientific™ Transcend™ DSX-1 SystemThermo Scientific™ UltiMate™ 3000 Biocompatible Rapid Separation BioRS Dual SystemThermo Scientific™ UltiMate™ 3000 Basic Manual SystemThermo Scientific™ Vanquish™ Flex Quaternary UHPLC System
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Catalog NumberIQLAAAGABHFAPUMZZZIQLAAEGACWFAKWMBMMIQLAAAGABHFAPBMBFFIQLAAAGABHFAPBMBFBIQLAAAGABHFAPUMBHV
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DescriptionUse the Thermo Scientific™ Vanquish™ Duo UHPLC Systems to support four workflows (Dual LC, Tandem LC or LC-MS, Transcend Duo LX-2 and Inverse Gradient) by combining two flow paths in one integrated UHPLC solution. These workflows improve your productivity by saving time, reducing cost per sample, ... Read MoreRedefine the traditional, labor-intensive, dried matrix spot analysis workflow with the Thermo Scientific Transcend DSX-1 UHPLC system. The fully automated system for toxicology and anti-doping laboratories enables automation and efficient online extraction and enrichment, while delivering sample ... Read MoreThe Thermo Scientific ™ UltiMate™ 3000 BioRS Dual System offers outstanding LC and advanced bio-UHPLC capabilities. Two independently operating gradient pumps and smart column switching save time. Offline fractionation combines noncompatible chemistries in one workflow. With our unique fractionation... Read MoreThe Thermo Scientific™ UltiMate™ 3000 Basic Manual system offers unique LC and entry level UHPLC capabilities without compromising on quality and robustness.The Thermo Scientific™ Vanquish™ Flex Quaternary system provides state-of-the-art quaternary solvent blending. As a member of the Thermo Scientific Vanquish UHPLC product line, the Vanquish Flex Quaternary system delivers new benchmarks in accuracy, precision, and sensitivity with a state-of-the-art... Read More
QuantityEAEAEAEAEA
Flow RateInquireInquire8 mL/min10 mL/min8 mL/min
Max. Pressure1500 bar (22,000 psi)Inquire103.4 Mpa or 1034 bar or 15000 psi62 Mpa / 620 bar / 9000 psiup to 1000 bar (15,000psi)
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