Ultra High Performance Liquid Chromatograph (UHPLC)

Ultra high-performance liquid chromatography, UHPLC, uses columns packed with porous sub-2-µm particles (usually 1.8 µm) to vastly increase throughput and resolving power compared to conventional 5-µm columns. Pressures can surpass 19,000 psi. Limited solvent consumption, the ability to work under a broader pressure range, and lower band broadening are further enhancements. UHPLC’s 10× reduction in analysis time strengthens its popularity in areas including the pharmaceutical industry, food safety, and the clinical field. The choice of detectors for use with UHPLC is wide-ranging, including UV-VIS, fluorescence, photodiode array, ELSD, quadrupole, and most recently, refractive index. For flexibility, many instruments offer the ability to run both conventional and UHPLC on one instrument. A final tip: When making the switch from HPLC to UHPLC, resist the temptation to overload the smaller columns.

Discover and compare Ultra High Performance Liquid Chromatographs:

CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ Vanquish™ Flex Binary UHPLC SystemThermo Scientific™ UltiMate™ 3000 Basic Automated SystemThermo Scientific™ UltiMate™ 3000 Basic Manual SystemThermo Scientific™ UltiMate™ 3000 Rapid Separation RS Dual SystemThermo Scientific™ Vanquish™ Duo UHPLC Systems
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Catalog NumberIQLAAAGABHFAPUMBJCIQLAAAGABHFAPBMBFCIQLAAAGABHFAPBMBFBIQLAAAGABHFAPBMBFEIQLAAAGABHFAPUMZZZ
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DescriptionThe Thermo Scientific™ Vanquish™ Flex Binary UHPLC system is biocompatible with a state-of-the-art binary high-pressure pump and state-of-the-art binary solvent blending. This ultra high performance liquid chromatography system shares all Vanquish values, such as a design focused on uptime, ... Read MoreThe Thermo Scientific™ UltiMate™ 3000 Automated system offers unique LC and entry level UHPLC capabilities without compromise. The integrated autosampler and thermostatted column compartment deliver retention time precision and the ability to fine tune backpressure, resolution and speed. With ... Read MoreThe Thermo Scientific™ UltiMate™ 3000 Basic Manual system offers unique LC and entry level UHPLC capabilities without compromising on quality and robustness.The Thermo Scientific ™ UltiMate™ 3000 Rapid Separation RS Dual System can, for example, inject the same sample into 2 flow paths and columns. With its two fully integrated, independently operating gradient pumps and smart column switching, it allows fast configuration of online-SPE, parallel or ... Read MoreUse the Thermo Scientific™ Vanquish™ Duo UHPLC Systems to support four workflows (Dual LC, Tandem LC or LC-MS, Transcend Duo LX-2 and Inverse Gradient) by combining two flow paths in one integrated UHPLC solution. These workflows improve your productivity by saving time, reducing cost per sample, ... Read More
QuantityEAEAEAEAEA
Flow Rate8 mL/min10 mL/min10 mL/min8 mL/minInquire
Max. Pressureup to 1000 bar (15,000psi)62 Mpa / 620 bar / 9000 psi62 Mpa / 620 bar / 9000 psi103.4 Mpa or 1034 bar or 15000 psi1500 bar (22,000 psi)
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