Ultra High Performance Liquid Chromatograph (UHPLC)

Ultra high-performance liquid chromatography, UHPLC, uses columns packed with porous sub-2-µm particles (usually 1.8 µm) to vastly increase throughput and resolving power compared to conventional 5-µm columns. Pressures can surpass 19,000 psi. Limited solvent consumption, the ability to work under a broader pressure range, and lower band broadening are further enhancements. UHPLC’s 10× reduction in analysis time strengthens its popularity in areas including the pharmaceutical industry, food safety, and the clinical field. The choice of detectors for use with UHPLC is wide-ranging, including UV-VIS, fluorescence, photodiode array, ELSD, quadrupole, and most recently, refractive index. For flexibility, many instruments offer the ability to run both conventional and UHPLC on one instrument. A final tip: When making the switch from HPLC to UHPLC, resist the temptation to overload the smaller columns.

Discover and compare Ultra High Performance Liquid Chromatographs:

CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ UltiMate™ 3000 Biocompatible Rapid Separation BioRS Dual SystemThermo Scientific™ UltiMate™ 3000 Biocompatible Rapid Separation BioRS SystemThermo Scientific™ UltiMate™ 3000 Rapid Separation RS Dual SystemThermo Scientific™ Vanquish™ Flex Quaternary UHPLC SystemThermo Scientific™ Vanquish™ LC Systems
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Catalog NumberIQLAAAGABHFAPBMBFFIQLAAAGADGFAMIMBCOIQLAAAGABHFAPBMBFEIQLAAAGABHFAPUMBHVIQLAAAGABHFAPUMZZZ
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DescriptionThe Thermo Scientific ™ UltiMate™ 3000 BioRS Dual System offers outstanding LC and advanced bio-UHPLC capabilities. Two independently operating gradient pumps and smart column switching save time. Offline fractionation combines noncompatible chemistries in one workflow. With our unique fractionation... Read MoreThe Thermo Scientific™ UltiMate™ 3000 BioRS System offers true bio-UHPLC capabilities with completely stainless steel-free flow path and newly developed, small particle and high-resolution bio-columns. Near-zero dead volume, Thermo Scientific™ Viper™ connection technology preserves peak sharpness ... Read MoreThe Thermo Scientific ™ UltiMate™ 3000 Rapid Separation RS Dual System can, for example, inject the same sample into 2 flow paths and columns. With its two fully integrated, independently operating gradient pumps and smart column switching, it allows fast configuration of online-SPE, parallel or ... Read MoreThe Thermo Scientific™ Vanquish™ Flex Quaternary system provides state-of-the-art quaternary solvent blending. As a member of the Thermo Scientific Vanquish UHPLC product line, the Vanquish Flex Quaternary system delivers new benchmarks in accuracy, precision, and sensitivity with a state-of-the-art... Read MoreToday’s scientists deserve the best analytical tools available; tools that empower to achieve the next scientific breakthrough, measure the previously unmeasurable or deliver outstanding quality results dependably. The Vanquish systems improve performance and repeatability with no trade-offs in ... Read More
QuantityEAEAEAEAEA
Flow Rate8 mL/min8 mL/min8 mL/min8 mL/min8 mL/min
Max. Pressure103.4 Mpa or 1034 bar or 15000 psiup to 1000 bar (15,000psi)103.4 Mpa or 1034 bar or 15000 psiup to 1000 bar (15,000psi)up to 1000 bar (15,000psi)
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